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RTP801/REDD1 Is Involved in Neuroinflammation and Modulates Cognitive Dysfunction in Huntington's Disease.
Pérez-Sisqués L, Solana-Balaguer J, Campoy-Campos G, Martín-Flores N, Sancho-Balsells A, Vives-Isern M, Soler-Palazón F, Garcia-Forn M, Masana M, Alberch J, Pérez-Navarro E, Giralt A, Malagelada C. Pérez-Sisqués L, et al. Among authors: malagelada c. Biomolecules. 2021 Dec 27;12(1):34. doi: 10.3390/biom12010034. Biomolecules. 2021. PMID: 35053183 Free PMC article.
Parkin loss of function contributes to RTP801 elevation and neurodegeneration in Parkinson's disease.
Romaní-Aumedes J, Canal M, Martín-Flores N, Sun X, Pérez-Fernández V, Wewering S, Fernández-Santiago R, Ezquerra M, Pont-Sunyer C, Lafuente A, Alberch J, Luebbert H, Tolosa E, Levy OA, Greene LA, Malagelada C. Romaní-Aumedes J, et al. Among authors: malagelada c. Cell Death Dis. 2014 Aug 7;5(8):e1364. doi: 10.1038/cddis.2014.333. Cell Death Dis. 2014. PMID: 25101677 Free PMC article.
RTP801 Is Involved in Mutant Huntingtin-Induced Cell Death.
Martín-Flores N, Romaní-Aumedes J, Rué L, Canal M, Sanders P, Straccia M, Allen ND, Alberch J, Canals JM, Pérez-Navarro E, Malagelada C. Martín-Flores N, et al. Among authors: malagelada c. Mol Neurobiol. 2016 Jul;53(5):2857-2868. doi: 10.1007/s12035-015-9166-6. Epub 2015 Apr 16. Mol Neurobiol. 2016. PMID: 25876513 Free article.
Chelerythrine promotes Ca2+-dependent calpain activation in neuronal cells in a PKC-independent manner.
Saavedra A, Fernández-García S, Cases S, Puigdellívol M, Alcalá-Vida R, Martín-Flores N, Alberch J, Ginés S, Malagelada C, Pérez-Navarro E. Saavedra A, et al. Among authors: malagelada c. Biochim Biophys Acta Gen Subj. 2017 Apr;1861(4):922-935. doi: 10.1016/j.bbagen.2017.01.021. Epub 2017 Jan 24. Biochim Biophys Acta Gen Subj. 2017. PMID: 28130160
Increased Levels of Rictor Prevent Mutant Huntingtin-Induced Neuronal Degeneration.
Creus-Muncunill J, Rué L, Alcalá-Vida R, Badillos-Rodríguez R, Romaní-Aumedes J, Marco S, Alberch J, Perez-Otaño I, Malagelada C, Pérez-Navarro E. Creus-Muncunill J, et al. Among authors: malagelada c. Mol Neurobiol. 2018 Oct;55(10):7728-7742. doi: 10.1007/s12035-018-0956-5. Epub 2018 Feb 19. Mol Neurobiol. 2018. PMID: 29460266 Free article.
SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinson's Disease.
Fernández-Santiago R, Martín-Flores N, Antonelli F, Cerquera C, Moreno V, Bandres-Ciga S, Manduchi E, Tolosa E, Singleton AB, Moore JH; International Parkinson's Disease Genomics Consortium; Martí MJ, Ezquerra M, Malagelada C. Fernández-Santiago R, et al. Among authors: malagelada c. Mov Disord. 2019 Sep;34(9):1333-1344. doi: 10.1002/mds.27770. Epub 2019 Jun 24. Mov Disord. 2019. PMID: 31234232 Free PMC article.
Increased translation as a novel pathogenic mechanism in Huntington's disease.
Creus-Muncunill J, Badillos-Rodríguez R, Garcia-Forn M, Masana M, Garcia-Díaz Barriga G, Guisado-Corcoll A, Alberch J, Malagelada C, Delgado-García JM, Gruart A, Pérez-Navarro E. Creus-Muncunill J, et al. Among authors: malagelada c. Brain. 2019 Oct 1;142(10):3158-3175. doi: 10.1093/brain/awz230. Brain. 2019. PMID: 31365052 Free article.
97 results