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Page 1
Differential Kinase Activity Across Prostate Tumor Compartments Defines Sensitivity to Target Inhibition.
Karabacak NM, Zheng Y, Dubash TD, Burr R, Micalizzi DS, Wittner BS, Lin M, Wiley DF, Comaills V, Emmons E, Niederhoffer KL, Ho U, Ukleja J, Che D, Stowe H, Nieman LT, Haas W, Stott SL, Lawrence MS, Ting DT, Miyamoto DT, Haber DA, Toner M, Maheswaran S. Karabacak NM, et al. Among authors: comaills v. Cancer Res. 2022 Mar 15;82(6):1084-1097. doi: 10.1158/0008-5472.CAN-21-2609. Cancer Res. 2022. PMID: 35045985 Free PMC article.
AR Expression in Breast Cancer CTCs Associates with Bone Metastases.
Aceto N, Bardia A, Wittner BS, Donaldson MC, O'Keefe R, Engstrom A, Bersani F, Zheng Y, Comaills V, Niederhoffer K, Zhu H, Mackenzie O, Shioda T, Sgroi D, Kapur R, Ting DT, Moy B, Ramaswamy S, Toner M, Haber DA, Maheswaran S. Aceto N, et al. Among authors: comaills v. Mol Cancer Res. 2018 Apr;16(4):720-727. doi: 10.1158/1541-7786.MCR-17-0480. Epub 2018 Feb 16. Mol Cancer Res. 2018. PMID: 29453314 Free PMC article.
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis.
Ebright RY, Lee S, Wittner BS, Niederhoffer KL, Nicholson BT, Bardia A, Truesdell S, Wiley DF, Wesley B, Li S, Mai A, Aceto N, Vincent-Jordan N, Szabolcs A, Chirn B, Kreuzer J, Comaills V, Kalinich M, Haas W, Ting DT, Toner M, Vasudevan S, Haber DA, Maheswaran S, Micalizzi DS. Ebright RY, et al. Among authors: comaills v. Science. 2020 Mar 27;367(6485):1468-1473. doi: 10.1126/science.aay0939. Epub 2020 Feb 6. Science. 2020. PMID: 32029688 Free PMC article.
COX-2 mediates tumor-stromal prolactin signaling to initiate tumorigenesis.
Zheng Y, Comaills V, Burr R, Boulay G, Miyamoto DT, Wittner BS, Emmons E, Sil S, Koulopoulos MW, Broderick KT, Tai E, Rengarajan S, Kulkarni AS, Shioda T, Wu CL, Ramaswamy S, Ting DT, Toner M, Rivera MN, Maheswaran S, Haber DA. Zheng Y, et al. Among authors: comaills v. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5223-5232. doi: 10.1073/pnas.1819303116. Epub 2019 Feb 28. Proc Natl Acad Sci U S A. 2019. PMID: 30819896 Free PMC article.
NR4A1 regulates expression of immediate early genes, suppressing replication stress in cancer.
Guo H, Golczer G, Wittner BS, Langenbucher A, Zachariah M, Dubash TD, Hong X, Comaills V, Burr R, Ebright RY, Horwitz E, Vuille JA, Hajizadeh S, Wiley DF, Reeves BA, Zhang JM, Niederhoffer KL, Lu C, Wesley B, Ho U, Nieman LT, Toner M, Vasudevan S, Zou L, Mostoslavsky R, Maheswaran S, Lawrence MS, Haber DA. Guo H, et al. Among authors: comaills v. Mol Cell. 2021 Oct 7;81(19):4041-4058.e15. doi: 10.1016/j.molcel.2021.09.016. Mol Cell. 2021. PMID: 34624217 Free PMC article.
Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility.
Yu M, Bardia A, Aceto N, Bersani F, Madden MW, Donaldson MC, Desai R, Zhu H, Comaills V, Zheng Z, Wittner BS, Stojanov P, Brachtel E, Sgroi D, Kapur R, Shioda T, Ting DT, Ramaswamy S, Getz G, Iafrate AJ, Benes C, Toner M, Maheswaran S, Haber DA. Yu M, et al. Among authors: comaills v. Science. 2014 Jul 11;345(6193):216-20. doi: 10.1126/science.1253533. Science. 2014. PMID: 25013076 Free PMC article.
Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition.
Comaills V, Kabeche L, Morris R, Buisson R, Yu M, Madden MW, LiCausi JA, Boukhali M, Tajima K, Pan S, Aceto N, Sil S, Zheng Y, Sundaresan T, Yae T, Jordan NV, Miyamoto DT, Ting DT, Ramaswamy S, Haas W, Zou L, Haber DA, Maheswaran S. Comaills V, et al. Cell Rep. 2016 Dec 6;17(10):2632-2647. doi: 10.1016/j.celrep.2016.11.022. Cell Rep. 2016. PMID: 27926867 Free PMC article.
Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination.
Zheng Y, Miyamoto DT, Wittner BS, Sullivan JP, Aceto N, Jordan NV, Yu M, Karabacak NM, Comaills V, Morris R, Desai R, Desai N, Emmons E, Milner JD, Lee RJ, Wu CL, Sequist LV, Haas W, Ting DT, Toner M, Ramaswamy S, Maheswaran S, Haber DA. Zheng Y, et al. Among authors: comaills v. Nat Commun. 2017 Feb 9;8:14344. doi: 10.1038/ncomms14344. Nat Commun. 2017. PMID: 28181495 Free PMC article.
SETD1A protects from senescence through regulation of the mitotic gene expression program.
Tajima K, Matsuda S, Yae T, Drapkin BJ, Morris R, Boukhali M, Niederhoffer K, Comaills V, Dubash T, Nieman L, Guo H, Magnus NKC, Dyson N, Shioda T, Haas W, Haber DA, Maheswaran S. Tajima K, et al. Among authors: comaills v. Nat Commun. 2019 Jun 28;10(1):2854. doi: 10.1038/s41467-019-10786-w. Nat Commun. 2019. PMID: 31253781 Free PMC article.
Homeobox B9 induces epithelial-to-mesenchymal transition-associated radioresistance by accelerating DNA damage responses.
Chiba N, Comaills V, Shiotani B, Takahashi F, Shimada T, Tajima K, Winokur D, Hayashida T, Willers H, Brachtel E, Vivanco MD, Haber DA, Zou L, Maheswaran S. Chiba N, et al. Among authors: comaills v. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2760-5. doi: 10.1073/pnas.1018867108. Epub 2011 Sep 19. Proc Natl Acad Sci U S A. 2012. PMID: 21930940 Free PMC article.
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