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Targeting Squalene Epoxidase Interrupts Homologous Recombination via the ER Stress Response and Promotes Radiotherapy Efficacy.
Hong Z, Liu T, Wan L, Fa P, Kumar P, Cao Y, Prasad CB, Qiu Z, Liu J, Wang H, Li Z, Wang QE, Guo P, Guo D, Yilmaz AS, Lu L, Papandreou I, Jacob NK, Yan C, Zhang X, She QB, Ma Z, Zhang J. Hong Z, et al. Among authors: jacob nk. Cancer Res. 2022 Apr 1;82(7):1298-1312. doi: 10.1158/0008-5472.CAN-21-2229. Cancer Res. 2022. PMID: 35045984 Free PMC article.
Genetic validation of the protein arginine methyltransferase PRMT5 as a candidate therapeutic target in glioblastoma.
Yan F, Alinari L, Lustberg ME, Martin LK, Cordero-Nieves HM, Banasavadi-Siddegowda Y, Virk S, Barnholtz-Sloan J, Bell EH, Wojton J, Jacob NK, Chakravarti A, Nowicki MO, Wu X, Lapalombella R, Datta J, Yu B, Gordon K, Haseley A, Patton JT, Smith PL, Ryu J, Zhang X, Mo X, Marcucci G, Nuovo G, Kwon CH, Byrd JC, Chiocca EA, Li C, Sif S, Jacob S, Lawler S, Kaur B, Baiocchi RA. Yan F, et al. Among authors: jacob s, jacob nk. Cancer Res. 2014 Mar 15;74(6):1752-65. doi: 10.1158/0008-5472.CAN-13-0884. Epub 2014 Jan 22. Cancer Res. 2014. PMID: 24453002 Free PMC article.
Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation.
Gasparini P, Lovat F, Fassan M, Casadei L, Cascione L, Jacob NK, Carasi S, Palmieri D, Costinean S, Shapiro CL, Huebner K, Croce CM. Gasparini P, et al. Among authors: jacob nk. Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):4536-41. doi: 10.1073/pnas.1402604111. Epub 2014 Mar 10. Proc Natl Acad Sci U S A. 2014. PMID: 24616504 Free PMC article.
Plasma-based biomaterials for the treatment of cutaneous radiation injury.
Miller ED, Song F, Smith JD, Ayan AS, Mo X, Weldon M, Lu L, Campbell PG, Bhatt AD, Chakravarti A, Jacob NK. Miller ED, et al. Among authors: jacob nk. Wound Repair Regen. 2019 Mar;27(2):139-149. doi: 10.1111/wrr.12691. Epub 2018 Dec 21. Wound Repair Regen. 2019. PMID: 30576033 Free PMC article.
Two-miRNA-based finger-stick assay for estimation of absorbed ionizing radiation dose.
Yadav M, Bhayana S, Liu J, Lu L, Huang J, Ma Y, Qamri Z, Mo X, Jacob DS, Parasa ST, Bhuiya N, Fadda P, Xu-Welliver M, Chakravarti A, Jacob NK. Yadav M, et al. Among authors: jacob nk. Sci Transl Med. 2020 Jul 15;12(552):eaaw5831. doi: 10.1126/scitranslmed.aaw5831. Sci Transl Med. 2020. PMID: 32669422 Free PMC article.
Disruption of DNA Repair and Survival Pathways through Heat Shock Protein Inhibition by Onalespib to Sensitize Malignant Gliomas to Chemoradiation Therapy.
Xu J, Wu PJ, Lai TH, Sharma P, Canella A, Welker AM, Beattie CE, Elder JB, Easley M, Lonser R, Jacob NK, Pietrzak M, Timmers CM, Lang F, Sampath D, Puduvalli VK. Xu J, et al. Among authors: jacob nk. Clin Cancer Res. 2022 May 2;28(9):1979-1990. doi: 10.1158/1078-0432.CCR-20-0468. Clin Cancer Res. 2022. PMID: 35140124 Free PMC article.
42 results