Schellens JHM - Search Results

1

Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients.

Aviles P, Altares R, van Andel L, Lubomirov R, Fudio S, Rosing H, Márquez Del Pino FM, Tibben MM, Benedit G, Nan-Offeringa L, Luepke Estefan XE, Francesch A, Zeaiter A, Cuevas C, Schellens JHM, Beijnen JH. Aviles P, et al. Among authors: schellens jhm. Drug Metab Dispos. 2022 Apr;50(4):327-340. doi: 10.1124/dmd.121.000668. Epub 2022 Jan 18. Drug Metab Dispos. 2022. PMID: 35042701

2

Entrapment by Cremophor EL decreases the absorption of paclitaxel from the gut.

Bardelmeijer HA, Ouwehand M, Malingré MM, Schellens J, Beijnen JH, van Tellingen O. Bardelmeijer HA, et al. Cancer Chemother Pharmacol. 2002 Feb;49(2):119-25. doi: 10.1007/s00280-001-0394-2. Epub 2001 Nov 20. Cancer Chemother Pharmacol. 2002. PMID: 11862425

3

Topoisomerase I levels in white blood cells of patients with ovarian cancer treated with paclitaxel-cisplatin-topotecan in a phase I study.

Schoemaker NE, Herben VM, de Jong LA, van Waardenburg RC, Pluim D, ten Bokkel Huinink WW, Beijnen JH, Schellens JH. Schoemaker NE, et al. Anticancer Drugs. 2002 Jan;13(1):87-91. doi: 10.1097/00001813-200201000-00010. Anticancer Drugs. 2002. PMID: 11914645

4

Clinical pharmacology of the novel marine-derived anticancer agent Ecteinascidin 743 administered as a 1- and 3-h infusion in a phase I study.

van Kesteren C, Twelves C, Bowman A, Hoekman K, López-Lázaro L, Jimeno J, Guzman C, Mathôt RA, Simpson A, Vermorken JB, Smyth J, Schellens JH, Hillebrand MJ, Rosing H, Beijnen JH. van Kesteren C, et al. Anticancer Drugs. 2002 Apr;13(4):381-93. doi: 10.1097/00001813-200204000-00007. Anticancer Drugs. 2002. PMID: 11984084 Clinical Trial.

5

Evaluation of the bioequivalence of tablets and capsules containing the novel anticancer agent R115777 (Zarnestra) in patients with advanced solid tumors.

Crul M, de Klerk GJ, Swart M, Weiner L, Palmer PA, Bol CJ, Beijnen JH, Schellens JH. Crul M, et al. Eur J Drug Metab Pharmacokinet. 2002 Jan-Mar;27(1):61-5. doi: 10.1007/BF03190407. Eur J Drug Metab Pharmacokinet. 2002. PMID: 11996329 Clinical Trial.

6

Acute poisoning after oral intake of a toluene-containing paint thinner.

Malingré MM, Hendrix EA, Schellens JH, Koks CH, Tibben MM, Challa EE, Beijnen JH. Malingré MM, et al. Eur J Pediatr. 2002 Jun;161(6):354-5. doi: 10.1007/s00431-001-0889-1. Epub 2002 Apr 16. Eur J Pediatr. 2002. PMID: 12029459 No abstract available.

7

Phase I clinical and pharmacologic study of chronic oral administration of the farnesyl protein transferase inhibitor R115777 in advanced cancer.

Crul M, de Klerk GJ, Swart M, van't Veer LJ, de Jong D, Boerrigter L, Palmer PA, Bol CJ, Tan H, de Gast GC, Beijnen JH, Schellens JH. Crul M, et al. J Clin Oncol. 2002 Jun 1;20(11):2726-35. doi: 10.1200/JCO.2002.09.116. J Clin Oncol. 2002. PMID: 12039935 Clinical Trial.

8

Bayesian pharmacokinetics of lithium after an acute self-intoxication and subsequent haemodialysis: a case report.

Kerbusch T, Mathôt RA, Otten HM, Meesters EW, van Kan HJ, Schellens JH, Beijnen JH. Kerbusch T, et al. Pharmacol Toxicol. 2002 May;90(5):243-5. doi: 10.1034/j.1600-0773.2002.900503.x. Pharmacol Toxicol. 2002. PMID: 12076304

9

Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.

Kruijtzer CM, Beijnen JH, Rosing H, ten Bokkel Huinink WW, Schot M, Jewell RC, Paul EM, Schellens JH. Kruijtzer CM, et al. J Clin Oncol. 2002 Jul 1;20(13):2943-50. doi: 10.1200/JCO.2002.12.116. J Clin Oncol. 2002. PMID: 12089223 Clinical Trial.

10

Determination of total platinum in plasma and plasma ultrafiltrate, from subjects dosed with the platinum-containing N-(2-hydroxypropyl)methacrylamide copolymer AP5280, by use of graphite-furnace Zeeman atomic-absorption spectrometry.

Tibben MM, Rademaker-Lakhai JM, Rice JR, Stewart DR, Schellens JH, Beijnen JH. Tibben MM, et al. Anal Bioanal Chem. 2002 Jul;373(4-5):233-6. doi: 10.1007/s00216-002-1340-9. Epub 2002 Jun 6. Anal Bioanal Chem. 2002. PMID: 12110973

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