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Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients.
Drug Metab Dispos. 2022 Apr;50(4):327-340. doi: 10.1124/dmd.121.000668. Epub 2022 Jan 18.
Drug Metab Dispos. 2022.
PMID: 35042701
Development and validation of a liquid chromatography-tandem mass spectrometry assay for the quantification of lurbinectedin in human plasma and urine.
van Andel L, Rosing H, Lubomirov R, Avilés P, Fudio S, Tibben MM, Nan-Offeringa L, Schellens JHM, Beijnen JH.
van Andel L, et al. Among authors: nan offeringa l.
J Pharm Biomed Anal. 2018 Sep 5;158:160-165. doi: 10.1016/j.jpba.2018.05.053. Epub 2018 Jun 1.
J Pharm Biomed Anal. 2018.
PMID: 29883879
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An excretion balance and pharmacokinetic study of the novel anticancer agent E7070 in cancer patients.
van sen Bongard HJ, Pluim D, Rosing H, Nan-Offeringa L, Schot M, Ravic M, Schellens JH, Beijnen JH.
van sen Bongard HJ, et al. Among authors: nan offeringa l.
Anticancer Drugs. 2002 Sep;13(8):807-14. doi: 10.1097/00001813-200209000-00004.
Anticancer Drugs. 2002.
PMID: 12394264
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Quantitative analysis of ES-285, an investigational marine anticancer drug, in human, mouse, rat, and dog plasma using coupled liquid chromatography and tandem mass spectrometry.
Stokvis E, Nan-Offeringa L, Rosing H, López-Lázaro L, Aceña JL, Miranda E, Lyubimov A, Levine BS, D'Aleo C, Schellens JH, Beijnen JH.
Stokvis E, et al. Among authors: nan offeringa l.
J Mass Spectrom. 2003 May;38(5):548-54. doi: 10.1002/jms.469.
J Mass Spectrom. 2003.
PMID: 12794877
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Quantitative analysis of D-24851, a novel anticancer agent, in human plasma and urine by liquid chromatography coupled with tandem mass spectrometry.
Stokvis E, Nan-Offeringa LG, Ouwehand M, Tibben MM, Rosing H, Schnaars Y, Grigat M, Romeis P, Schellens JH, Beijnen JH.
Stokvis E, et al. Among authors: nan offeringa lg.
Rapid Commun Mass Spectrom. 2004;18(13):1465-71. doi: 10.1002/rcm.1493.
Rapid Commun Mass Spectrom. 2004.
PMID: 15216507
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Quantitative determination of the novel anticancer drug E7070 (indisulam) and its metabolite (1,4-benzenedisulphonamide) in human plasma, urine and faeces by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
Beumer JH, Rosing H, Hillebrand MJ, Nan-Offeringa LG, Foley K, Yule SM, Heck AJ, Schellens JH, Beijnen JH.
Beumer JH, et al. Among authors: nan offeringa lg.
Rapid Commun Mass Spectrom. 2004;18(23):2839-48. doi: 10.1002/rcm.1699.
Rapid Commun Mass Spectrom. 2004.
PMID: 15517526
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Rapid quantification of HIV protease inhibitors in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
Crommentuyn KM, Rosing H, Nan-Offeringa LG, Hillebrand MJ, Huitema AD, Beijnen JH.
Crommentuyn KM, et al. Among authors: nan offeringa lg.
J Mass Spectrom. 2003 Feb;38(2):157-66. doi: 10.1002/jms.425.
J Mass Spectrom. 2003.
PMID: 12577282
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