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Outcomes and clinical characteristics of the compassionate use of plitidepsin in COVID-19 patients with solid tumours, haematological malignancies or anti-CD20 antibody treatment.
Aguareles J, Villares Fernández P, Forné C, Martí-Ballesteros EM, Pradillo Fernández V, Sotres-Fernandez G, de la Fuente-Burguera A, Navarro-San Francisco C, Buzón-Martín LM, García-Delangue T, Aiello FT, Carnevali-Ruiz D, Lloris R, Luepke-Estefan XE, López-Martín JA, Jimeno JM, García-Casas A, Guisado-Vasco P. Aguareles J, et al. Among authors: luepke estefan xe. Infect Dis (Lond). 2024 May 14:1-6. doi: 10.1080/23744235.2024.2351043. Online ahead of print. Infect Dis (Lond). 2024. PMID: 38743059
Outcomes and clinical characteristics of the compassionate use of plitidepsin for immunocompromised adult patients with COVID-19.
Aguareles J, Fernández PV, Carralón-González MM, Izquierdo CF, Martí-Ballesteros EM, Fernández VP, Sotres-Fernandez G, García-Delangue T, LaPetra RGV, Sánchez-Manzano MD, Gutiérrez C, García-Coca M, Carnevali-Ruiz D, Barrena-Puertas R, Luque-Pinilla JM, Lloris R, Luepke-Estefan XE, López-Martín JA, Jimeno JM, Guisado-Vasco P. Aguareles J, et al. Among authors: luepke estefan xe. Int J Infect Dis. 2023 Oct;135:12-17. doi: 10.1016/j.ijid.2023.07.011. Epub 2023 Jul 21. Int J Infect Dis. 2023. PMID: 37481109 Free article.
Phase I study of lurbinectedin in combination with weekly paclitaxel with or without bevacizumab in patients with advanced solid tumors.
Calvo E, Sessa C, Harada G, de Miguel M, Kahatt C, Luepke-Estefan XE, Siguero M, Fernandez-Teruel C, Cullell-Young M, Stathis A, Drilon A. Calvo E, et al. Among authors: luepke estefan xe. Invest New Drugs. 2022 Dec;40(6):1263-1273. doi: 10.1007/s10637-022-01281-z. Epub 2022 Aug 10. Invest New Drugs. 2022. PMID: 35947247 Free PMC article. Clinical Trial.
Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients.
Aviles P, Altares R, van Andel L, Lubomirov R, Fudio S, Rosing H, Márquez Del Pino FM, Tibben MM, Benedit G, Nan-Offeringa L, Luepke Estefan XE, Francesch A, Zeaiter A, Cuevas C, Schellens JHM, Beijnen JH. Aviles P, et al. Among authors: luepke estefan xe. Drug Metab Dispos. 2022 Apr;50(4):327-340. doi: 10.1124/dmd.121.000668. Epub 2022 Jan 18. Drug Metab Dispos. 2022. PMID: 35042701
Plitidepsin as a successful rescue treatment for prolonged viral SARS-CoV-2 replication in a patient with previous anti-CD20 monoclonal antibody-mediated B cell depletion and chronic lymphocytic leukemia.
Guisado-Vasco P, Carralón-González MM, Aguareles-Gorines J, Martí-Ballesteros EM, Sánchez-Manzano MD, Carnevali-Ruiz D, García-Coca M, Barrena-Puertas R, de Viedma RG, Luque-Pinilla JM, Sotres-Fernandez G, Fernández-Sousa JM, Luepke-Estefan XE, López-Martín JA, Jimeno JM. Guisado-Vasco P, et al. Among authors: luepke estefan xe. J Hematol Oncol. 2022 Jan 10;15(1):4. doi: 10.1186/s13045-021-01220-0. J Hematol Oncol. 2022. PMID: 35012608 Free PMC article.
Plitidepsin for the management of a cancer patient infected with SARS-CoV-2 while receiving chemotherapy.
Guisado-Vasco P, González-Cortijo L, D'Errico G, Serrera-Alvarez A, Sotres-Fernandez G, García-Coca M, Fernández-Sousa JM, Luepke-Estefan XE, López-Martín JA, Jimeno JM. Guisado-Vasco P, et al. Among authors: luepke estefan xe. Ann Oncol. 2021 Oct;32(10):1295-1297. doi: 10.1016/j.annonc.2021.07.003. Epub 2021 Jul 7. Ann Oncol. 2021. PMID: 34242743 Free PMC article. No abstract available.