Hanessian S - Search Results

1

Backbone Hydrocarbon-Constrained Nucleic Acids Modulate Hybridization Kinetics for RNA.

Rajasekaran T, Freestone GC, Galindo-Murillo R, Lugato B, Rico L, Salinas JC, Gaus H, Migawa MT, Swayze EE, Cheatham TE 3rd, Hanessian S, Seth PP. Rajasekaran T, et al. Among authors: hanessian s. J Am Chem Soc. 2022 Feb 2;144(4):1941-1950. doi: 10.1021/jacs.1c12323. Epub 2022 Jan 18. J Am Chem Soc. 2022. PMID: 35041415 Free PMC article.

2

Total synthesis of bafilomycin A(1) relying on iterative 1,2-induction in acyclic precursors.

Hanessian S, Ma J, Wang W, Gai Y. Hanessian S, et al. J Am Chem Soc. 2001 Oct 24;123(42):10200-6. doi: 10.1021/ja011452u. J Am Chem Soc. 2001. PMID: 11603969

3

Total synthesis and structural confirmation of the marine natural product Dysinosin A: a novel inhibitor of thrombin and Factor VIIa.

Hanessian S, Margarita R, Hall A, Johnstone S, Tremblay M, Parlanti L. Hanessian S, et al. J Am Chem Soc. 2002 Nov 13;124(45):13342-3. doi: 10.1021/ja0208153. J Am Chem Soc. 2002. PMID: 12418860

4

Application of conformation design in acyclic stereoselection: total synthesis of borrelidin as the crystalline benzene solvate.

Hanessian S, Yang Y, Giroux S, Mascitti V, Ma J, Raeppel F. Hanessian S, et al. J Am Chem Soc. 2003 Nov 12;125(45):13784-92. doi: 10.1021/ja030139k. J Am Chem Soc. 2003. PMID: 14599218

5

The N-acyloxyiminium ion aza-Prins route to octahydroindoles: total synthesis and structural confirmation of the antithrombotic marine natural product oscillarin.

Hanessian S, Tremblay M, Petersen JF. Hanessian S, et al. J Am Chem Soc. 2004 May 19;126(19):6064-71. doi: 10.1021/ja030669g. J Am Chem Soc. 2004. PMID: 15137772

6

Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site.

François B, Szychowski J, Adhikari SS, Pachamuthu K, Swayze EE, Griffey RH, Migawa MT, Westhof E, Hanessian S. François B, et al. Among authors: hanessian s. Angew Chem Int Ed Engl. 2004 Dec 10;43(48):6735-8. doi: 10.1002/anie.200462092. Angew Chem Int Ed Engl. 2004. PMID: 15593140 No abstract available.

7

Total synthesis and structural confirmation of chlorodysinosin A.

Hanessian S, Del Valle JR, Xue Y, Blomberg N. Hanessian S, et al. J Am Chem Soc. 2006 Aug 16;128(32):10491-5. doi: 10.1021/ja0625834. J Am Chem Soc. 2006. PMID: 16895415

8

Structure-based design, synthesis, and A-site rRNA cocrystal complexes of functionally novel aminoglycoside antibiotics: C2" ether analogues of paromomycin.

Hanessian S, Szychowski J, Adhikari SS, Vasquez G, Kandasamy P, Swayze EE, Migawa MT, Ranken R, François B, Wirmer-Bartoschek J, Kondo J, Westhof E. Hanessian S, et al. J Med Chem. 2007 May 17;50(10):2352-69. doi: 10.1021/jm061200+. Epub 2007 Apr 26. J Med Chem. 2007. PMID: 17458946

9

Structure-based design, synthesis and A-site rRNA co-crystal complexes of novel amphiphilic aminoglycoside antibiotics with new binding modes: a synergistic hydrophobic effect against resistant bacteria.

Hanessian S, Pachamuthu K, Szychowski J, Giguère A, Swayze EE, Migawa MT, François B, Kondo J, Westhof E. Hanessian S, et al. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7097-101. doi: 10.1016/j.bmcl.2010.09.084. Epub 2010 Sep 19. Bioorg Med Chem Lett. 2010. PMID: 20970332

10

Structure-based design of a highly constrained nucleic acid analogue: improved duplex stabilization by restricting sugar pucker and torsion angle γ.

Hanessian S, Schroeder BR, Giacometti RD, Merner BL, Ostergaard M, Swayze EE, Seth PP. Hanessian S, et al. Angew Chem Int Ed Engl. 2012 Nov 5;51(45):11242-5. doi: 10.1002/anie.201203680. Epub 2012 Aug 22. Angew Chem Int Ed Engl. 2012. PMID: 22915274

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