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Upregulated Apelin Signaling in Pancreatic Cancer Activates Oncogenic Signaling Pathways to Promote Tumor Development.
Chaves-Almagro C, Auriau J, Dortignac A, Clerc P, Lulka H, Deleruyelle S, Projetti F, Nakhlé J, Frances A, Berta J, Gigoux V, Fourmy D, Dufresne M, Gomez-Brouchet A, Guillermet-Guibert J, Cordelier P, Knibiehler B, Jockers R, Valet P, Audigier Y, Masri B. Chaves-Almagro C, et al. Among authors: lulka h. Int J Mol Sci. 2022 Sep 13;23(18):10600. doi: 10.3390/ijms231810600. Int J Mol Sci. 2022. PMID: 36142542 Free PMC article.
Loss of Somatostatin Receptor Subtype 2 Promotes Growth of KRAS-Induced Pancreatic Tumors in Mice by Activating PI3K Signaling and Overexpression of CXCL16.
Chalabi-Dchar M, Cassant-Sourdy S, Duluc C, Fanjul M, Lulka H, Samain R, Roche C, Breibach F, Delisle MB, Poupot M, Dufresne M, Shimaoka T, Yonehara S, Mathonnet M, Pyronnet S, Bousquet C. Chalabi-Dchar M, et al. Among authors: lulka h. Gastroenterology. 2015 Jun;148(7):1452-65. doi: 10.1053/j.gastro.2015.02.009. Epub 2015 Feb 13. Gastroenterology. 2015. PMID: 25683115
First-in-man phase 1 clinical trial of gene therapy for advanced pancreatic cancer: safety, biodistribution, and preliminary clinical findings.
Buscail L, Bournet B, Vernejoul F, Cambois G, Lulka H, Hanoun N, Dufresne M, Meulle A, Vignolle-Vidoni A, Ligat L, Saint-Laurent N, Pont F, Dejean S, Gayral M, Martins F, Torrisani J, Barbey O, Gross F, Guimbaud R, Otal P, Lopez F, Tiraby G, Cordelier P. Buscail L, et al. Among authors: lulka h. Mol Ther. 2015 Apr;23(4):779-89. doi: 10.1038/mt.2015.1. Epub 2015 Jan 14. Mol Ther. 2015. PMID: 25586689 Free PMC article. Clinical Trial.
Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α.
Baer R, Cintas C, Dufresne M, Cassant-Sourdy S, Schönhuber N, Planque L, Lulka H, Couderc B, Bousquet C, Garmy-Susini B, Vanhaesebroeck B, Pyronnet S, Saur D, Guillermet-Guibert J. Baer R, et al. Among authors: lulka h. Genes Dev. 2014 Dec 1;28(23):2621-35. doi: 10.1101/gad.249409.114. Genes Dev. 2014. PMID: 25452273 Free PMC article.
MicroRNAs as emerging biomarkers and therapeutic targets for pancreatic cancer.
Gayral M, Jo S, Hanoun N, Vignolle-Vidoni A, Lulka H, Delpu Y, Meulle A, Dufresne M, Humeau M, Chalret du Rieu M, Bournet B, Sèlves J, Guimbaud R, Carrère N, Buscail L, Torrisani J, Cordelier P. Gayral M, et al. Among authors: lulka h. World J Gastroenterol. 2014 Aug 28;20(32):11199-209. doi: 10.3748/wjg.v20.i32.11199. World J Gastroenterol. 2014. PMID: 25170204 Free PMC article. Review.
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