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Inhibition of SARS-CoV-2 infection in human iPSC-derived cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoarchitecture and beating.
Salerno JA, Torquato T, Temerozo JR, Goto-Silva L, Karmirian K, Mendes MA, Sacramento CQ, Fintelman-Rodrigues N, Souza LRQ, Ornelas IM, Veríssimo CP, Aragão LGHS, Vitória G, Pedrosa CSG, da Silva Gomes Dias S, Cardoso Soares V, Puig-Pijuan T, Salazar V, Dariolli R, Biagi D, Furtado DR, Barreto Chiarini L, Borges HL, Bozza PT, Zaluar P Guimarães M, Souza TML, Rehen SK. Salerno JA, et al. Among authors: borges hl. PeerJ. 2021 Dec 20;9:e12595. doi: 10.7717/peerj.12595. eCollection 2021. PeerJ. 2021. PMID: 35036128 Free PMC article.
Non-permissive SARS-CoV-2 infection in human neurospheres.
Pedrosa CDSG, Goto-Silva L, Temerozo JR, Souza LRQ, Vitória G, Ornelas IM, Karmirian K, Mendes MA, Gomes IC, Sacramento CQ, Fintelman-Rodrigues N, Cardoso Soares V, Silva Gomes Dias SD, Salerno JA, Puig-Pijuan T, Oliveira JT, Aragão LGHS, Torquato TCQ, Veríssimo C, Biagi D, Cruvinel EM, Dariolli R, Furtado DR, Borges HL, Bozza PT, Rehen S, Moreno L Souza T, Guimarães MZP. Pedrosa CDSG, et al. Among authors: borges hl. Stem Cell Res. 2021 Jul;54:102436. doi: 10.1016/j.scr.2021.102436. Epub 2021 Jun 20. Stem Cell Res. 2021. PMID: 34186311 Free PMC article.
WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2.
Aragão LGHS, Oliveira JT, Temerozo JR, Mendes MA, Salerno JA, Pedrosa CSG, Puig-Pijuan T, Veríssimo CP, Ornelas IM, Torquato T, Vitória G, Sacramento CQ, Fintelman-Rodrigues N, da Silva Gomes Dias S, Cardoso Soares V, Souza LRQ, Karmirian K, Goto-Silva L, Biagi D, Cruvinel EM, Dariolli R, Furtado DR, Bozza PT, Borges HL, Souza TML, Guimarães MZP, Rehen SK. Aragão LGHS, et al. Among authors: borges hl. PeerJ. 2021 Oct 8;9:e12262. doi: 10.7717/peerj.12262. eCollection 2021. PeerJ. 2021. PMID: 34707939 Free PMC article.
Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes.
Ledur PF, Karmirian K, Pedrosa CDSG, Souza LRQ, Assis-de-Lemos G, Martins TM, Ferreira JCCG, de Azevedo Reis GF, Silva ES, Silva D, Salerno JA, Ornelas IM, Devalle S, Madeiro da Costa RF, Goto-Silva L, Higa LM, Melo A, Tanuri A, Chimelli L, Murata MM, Garcez PP, Filippi-Chiela EC, Galina A, Borges HL, Rehen SK. Ledur PF, et al. Among authors: borges hl. Sci Rep. 2020 Jan 27;10(1):1218. doi: 10.1038/s41598-020-57914-x. Sci Rep. 2020. PMID: 31988337 Free PMC article.
Non-permissive SARS-CoV-2 infection in human neurospheres.
Pedrosa CDSG, Goto-Silva L, Temerozo JR, Souza LRQ, Vitória G, Ornelas IM, Karmirian K, Mendes MA, Gomes IC, Sacramento CQ, Fintelman-Rodrigues N, Soares VC, Dias SDSG, Salerno JA, Puig-Pijuan T, Oliveira JT, Aragão LGHS, Torquato TCQ, Veríssimo C, Biagi D, Cruvinel EM, Dariolli R, Furtado DR, Borges HL, Bozza PT, Rehen S, Souza TML, Guimarães MZP. Pedrosa CDSG, et al. Among authors: borges hl. bioRxiv [Preprint]. 2021 Jun 17:2020.09.11.293951. doi: 10.1101/2020.09.11.293951. bioRxiv. 2021. PMID: 33052345 Free PMC article. Updated. Preprint.
Implications of aneuploidy for stem cell biology and brain therapeutics.
Devalle S, Sartore RC, Paulsen BS, Borges HL, Martins RA, Rehen SK. Devalle S, et al. Among authors: borges hl. Front Cell Neurosci. 2012 Sep 5;6:36. doi: 10.3389/fncel.2012.00036. eCollection 2012. Front Cell Neurosci. 2012. PMID: 22973193 Free PMC article.
Glioblastoma cells inhibit astrocytic p53-expression favoring cancer malignancy.
Biasoli D, Sobrinho MF, da Fonseca AC, de Matos DG, Romão L, de Moraes Maciel R, Rehen SK, Moura-Neto V, Borges HL, Lima FR. Biasoli D, et al. Among authors: borges hl. Oncogenesis. 2014 Oct 20;3(10):e123. doi: 10.1038/oncsis.2014.36. Oncogenesis. 2014. PMID: 25329722 Free PMC article.
39 results