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An adapted passive model of anti-MPO dependent crescentic glomerulonephritis reveals matrix dysregulation and is amenable to modulation by CXCR4 inhibition.
Fayçal CA, Oszwald A, Feilen T, Cosenza-Contreras M, Schilling O, Loustau T, Steinbach F, Schachner H, Langer B, Heeringa P, Rees AJ, Orend G, Kain R. Fayçal CA, et al. Among authors: heeringa p. Matrix Biol. 2022 Feb;106:12-33. doi: 10.1016/j.matbio.2022.01.001. Epub 2022 Jan 13. Matrix Biol. 2022. PMID: 35032611 Free article.
IgG glycan hydrolysis attenuates ANCA-mediated glomerulonephritis.
van Timmeren MM, van der Veen BS, Stegeman CA, Petersen AH, Hellmark T, Collin M, Heeringa P. van Timmeren MM, et al. Among authors: heeringa p. J Am Soc Nephrol. 2010 Jul;21(7):1103-14. doi: 10.1681/ASN.2009090984. Epub 2010 May 6. J Am Soc Nephrol. 2010. PMID: 20448018 Free PMC article.
Effects of p38 mitogen-activated protein kinase inhibition on anti-neutrophil cytoplasmic autoantibody pathogenicity in vitro and in vivo.
van der Veen BS, Chen M, Müller R, van Timmeren MM, Petersen AH, Lee PA, Satchell SC, Mathieson PW, Saleem MA, Stegeman CA, Zwerina J, Molema G, Heeringa P. van der Veen BS, et al. Among authors: heeringa p. Ann Rheum Dis. 2011 Feb;70(2):356-65. doi: 10.1136/ard.2010.129106. Epub 2010 Nov 9. Ann Rheum Dis. 2011. PMID: 21062851
Immune regulatory mechanisms in ANCA-associated vasculitides.
Lepse N, Abdulahad WH, Kallenberg CG, Heeringa P. Lepse N, et al. Among authors: heeringa p. Autoimmun Rev. 2011 Dec;11(2):77-83. doi: 10.1016/j.autrev.2011.08.002. Epub 2011 Aug 11. Autoimmun Rev. 2011. PMID: 21856453 Review.
High prevalence of autoantibodies to hLAMP-2 in anti-neutrophil cytoplasmic antibody-associated vasculitis.
Kain R, Tadema H, McKinney EF, Benharkou A, Brandes R, Peschel A, Hubert V, Feenstra T, Sengölge G, Stegeman C, Heeringa P, Lyons PA, Smith KG, Kallenberg C, Rees AJ. Kain R, et al. Among authors: heeringa p. J Am Soc Nephrol. 2012 Mar;23(3):556-66. doi: 10.1681/ASN.2011090920. Epub 2012 Feb 9. J Am Soc Nephrol. 2012. PMID: 22323643 Free PMC article.
203 results