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Molecular mechanism for differential recognition of membrane phosphatidylserine by the immune regulatory receptor Tim4.
Tietjen GT, Gong Z, Chen CH, Vargas E, Crooks JE, Cao KD, Heffern CT, Henderson JM, Meron M, Lin B, Roux B, Schlossman ML, Steck TL, Lee KY, Adams EJ. Tietjen GT, et al. Among authors: adams ej. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):E1463-72. doi: 10.1073/pnas.1320174111. Epub 2014 Mar 31. Proc Natl Acad Sci U S A. 2014. PMID: 24706780 Free PMC article.
MAIT recognition of a stimulatory bacterial antigen bound to MR1.
López-Sagaseta J, Dulberger CL, McFedries A, Cushman M, Saghatelian A, Adams EJ. López-Sagaseta J, et al. Among authors: adams ej. J Immunol. 2013 Nov 15;191(10):5268-77. doi: 10.4049/jimmunol.1301958. Epub 2013 Oct 9. J Immunol. 2013. PMID: 24108697 Free PMC article.
The 2.5 Å structure of CD1c in complex with a mycobacterial lipid reveals an open groove ideally suited for diverse antigen presentation.
Scharf L, Li NS, Hawk AJ, Garzón D, Zhang T, Fox LM, Kazen AR, Shah S, Haddadian EJ, Gumperz JE, Saghatelian A, Faraldo-Gómez JD, Meredith SC, Piccirilli JA, Adams EJ. Scharf L, et al. Among authors: adams ej. Immunity. 2010 Dec 14;33(6):853-62. doi: 10.1016/j.immuni.2010.11.026. Immunity. 2010. PMID: 21167756 Free PMC article.
The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins.
López-Sagaseta J, Dulberger CL, Crooks JE, Parks CD, Luoma AM, McFedries A, Van Rhijn I, Saghatelian A, Adams EJ. López-Sagaseta J, et al. Among authors: adams ej. Proc Natl Acad Sci U S A. 2013 May 7;110(19):E1771-8. doi: 10.1073/pnas.1222678110. Epub 2013 Apr 23. Proc Natl Acad Sci U S A. 2013. PMID: 23613577 Free PMC article.
269 results