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Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production.
Hulme BJ, Geyer KK, Forde-Thomas JE, Padalino G, Phillips DW, Ittiprasert W, Karinshak SE, Mann VH, Chalmers IW, Brindley PJ, Hokke CH, Hoffmann KF. Hulme BJ, et al. Among authors: geyer kk. PLoS Pathog. 2022 Jan 13;18(1):e1009828. doi: 10.1371/journal.ppat.1009828. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35025955 Free PMC article.
(Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach.
Cosseau C, Wolkenhauer O, Padalino G, Geyer KK, Hoffmann KF, Grunau C. Cosseau C, et al. Among authors: geyer kk. Trends Parasitol. 2017 Apr;33(4):285-294. doi: 10.1016/j.pt.2016.12.002. Epub 2016 Dec 28. Trends Parasitol. 2017. PMID: 28040375 Free PMC article. Review.
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets.
Whatley KCL, Padalino G, Whiteland H, Geyer KK, Hulme BJ, Chalmers IW, Forde-Thomas J, Ferla S, Brancale A, Hoffmann KF. Whatley KCL, et al. Among authors: geyer kk. PLoS Negl Trop Dis. 2019 Nov 15;13(11):e0007693. doi: 10.1371/journal.pntd.0007693. eCollection 2019 Nov. PLoS Negl Trop Dis. 2019. PMID: 31730617 Free PMC article.
The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni.
Geyer KK, Niazi UH, Duval D, Cosseau C, Tomlinson C, Chalmers IW, Swain MT, Cutress DJ, Bickham-Wright U, Munshi SE, Grunau C, Yoshino TP, Hoffmann KF. Geyer KK, et al. PLoS Negl Trop Dis. 2017 May 16;11(5):e0005246. doi: 10.1371/journal.pntd.0005246. eCollection 2017 May. PLoS Negl Trop Dis. 2017. PMID: 28510608 Free PMC article.
The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities.
Geyer KK, Munshi SE, Vickers M, Squance M, Wilkinson TJ, Berrar D, Chaparro C, Swain MT, Hoffmann KF. Geyer KK, et al. Int J Parasitol Drugs Drug Resist. 2018 Aug;8(2):213-222. doi: 10.1016/j.ijpddr.2018.03.006. Epub 2018 Apr 1. Int J Parasitol Drugs Drug Resist. 2018. PMID: 29649665 Free PMC article.
17 results