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Endothelial Piezo1 sustains muscle capillary density and contributes to physical activity.
Bartoli F, Debant M, Chuntharpursat-Bon E, Evans EL, Musialowski KE, Parsonage G, Morley LC, Futers TS, Sukumar P, Bowen TS, Kearney MT, Lichtenstein L, Roberts LD, Beech DJ. Bartoli F, et al. Among authors: parsonage g. J Clin Invest. 2022 Mar 1;132(5):e141775. doi: 10.1172/JCI141775. J Clin Invest. 2022. PMID: 35025768 Free PMC article.
Biological Effects of Modifications of the Englerin A Glycolate.
Seenadera SPD, Long SA, Akee R, Bermudez G, Parsonage G, Strope J, Peer C, Figg WD, Parker KA, Beech DJ, Beutler JA. Seenadera SPD, et al. Among authors: parsonage g. ACS Med Chem Lett. 2022 Aug 22;13(9):1472-1476. doi: 10.1021/acsmedchemlett.2c00258. eCollection 2022 Sep 8. ACS Med Chem Lett. 2022. PMID: 36105325 Free PMC article.
Improved PIEZO1 agonism through 4-benzoic acid modification of Yoda1.
Parsonage G, Cuthbertson K, Endesh N, Murciano N, Hyman AJ, Revill CH, Povstyan OV, Chuntharpursat-Bon E, Debant M, Ludlow MJ, Futers TS, Lichtenstein L, Kinsella JA, Bartoli F, Rotordam MG, Becker N, Brüggemann A, Foster R, Beech DJ. Parsonage G, et al. Br J Pharmacol. 2023 Aug;180(16):2039-2063. doi: 10.1111/bph.15996. Epub 2023 Jan 31. Br J Pharmacol. 2023. PMID: 36457143 Free PMC article.
Independent endothelial functions of PIEZO1 and TRPV4 in hepatic portal vein and predominance of PIEZO1 in mechanical and osmotic stress.
Endesh N, Chuntharpursat-Bon E, Revill C, Yuldasheva NY, Futers TS, Parsonage G, Humphreys N, Adamson A, Morley LC, Cubbon RM, Prasad KR, Foster R, Lichtenstein L, Beech DJ. Endesh N, et al. Among authors: parsonage g. Liver Int. 2023 Sep;43(9):2026-2038. doi: 10.1111/liv.15646. Epub 2023 Jun 22. Liver Int. 2023. PMID: 37349903 Free PMC article.
Differential expression, function and response to inflammatory stimuli of 11beta-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation.
Hardy RS, Filer A, Cooper MS, Parsonage G, Raza K, Hardie DL, Rabbitt EH, Stewart PM, Buckley CD, Hewison M. Hardy RS, et al. Among authors: parsonage g. Arthritis Res Ther. 2006;8(4):R108. doi: 10.1186/ar1993. Arthritis Res Ther. 2006. PMID: 16846535 Free PMC article.
26 results