Elledge SJ - Search Results

1

Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis.

Bjornevik K, Cortese M, Healy BC, Kuhle J, Mina MJ, Leng Y, Elledge SJ, Niebuhr DW, Scher AI, Munger KL, Ascherio A. Bjornevik K, et al. Among authors: elledge sj. Science. 2022 Jan 21;375(6578):296-301. doi: 10.1126/science.abj8222. Epub 2022 Jan 13. Science. 2022. PMID: 35025605 Free article.

2

A genetic screen for candidate tumor suppressors identifies REST.

Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B, Zhao JJ, Roberts TM, Mandel G, Hannon GJ, Depinho RA, Chin L, Elledge SJ. Westbrook TF, et al. Among authors: elledge sj. Cell. 2005 Jun 17;121(6):837-48. doi: 10.1016/j.cell.2005.03.033. Cell. 2005. PMID: 15960972 Free article.

3

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ. Matsuoka S, et al. Among authors: elledge sj. Science. 2007 May 25;316(5828):1160-6. doi: 10.1126/science.1140321. Science. 2007. PMID: 17525332

4

SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation.

Westbrook TF, Hu G, Ang XL, Mulligan P, Pavlova NN, Liang A, Leng Y, Maehr R, Shi Y, Harper JW, Elledge SJ. Westbrook TF, et al. Among authors: elledge sj. Nature. 2008 Mar 20;452(7185):370-4. doi: 10.1038/nature06780. Nature. 2008. PMID: 18354483 Free PMC article.

5

A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal.

Hu G, Kim J, Xu Q, Leng Y, Orkin SH, Elledge SJ. Hu G, et al. Among authors: elledge sj. Genes Dev. 2009 Apr 1;23(7):837-48. doi: 10.1101/gad.1769609. Genes Dev. 2009. PMID: 19339689 Free PMC article.

6

Global identification of modular cullin-RING ligase substrates.

Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ. Emanuele MJ, et al. Among authors: elledge sj. Cell. 2011 Oct 14;147(2):459-74. doi: 10.1016/j.cell.2011.09.019. Epub 2011 Sep 29. Cell. 2011. PMID: 21963094 Free PMC article.

7

A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors.

Izhar L, Adamson B, Ciccia A, Lewis J, Pontano-Vaites L, Leng Y, Liang AC, Westbrook TF, Harper JW, Elledge SJ. Izhar L, et al. Among authors: elledge sj. Cell Rep. 2015 Jun 9;11(9):1486-500. doi: 10.1016/j.celrep.2015.04.053. Epub 2015 May 21. Cell Rep. 2015. PMID: 26004182 Free PMC article.

8

A genetic interaction analysis identifies cancer drivers that modify EGFR dependency.

Liao S, Davoli T, Leng Y, Li MZ, Xu Q, Elledge SJ. Liao S, et al. Among authors: elledge sj. Genes Dev. 2017 Jan 15;31(2):184-196. doi: 10.1101/gad.291948.116. Epub 2017 Feb 6. Genes Dev. 2017. PMID: 28167502 Free PMC article.

9

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.

Mengwasser KE, Adeyemi RO, Leng Y, Choi MY, Clairmont C, D'Andrea AD, Elledge SJ. Mengwasser KE, et al. Among authors: elledge sj. Mol Cell. 2019 Mar 7;73(5):885-899.e6. doi: 10.1016/j.molcel.2018.12.008. Epub 2019 Jan 24. Mol Cell. 2019. PMID: 30686591 Free PMC article.

10

Tissue-specificity in cancer: The rule, not the exception.

Haigis KM, Cichowski K, Elledge SJ. Haigis KM, et al. Among authors: elledge sj. Science. 2019 Mar 15;363(6432):1150-1151. doi: 10.1126/science.aaw3472. Science. 2019. PMID: 30872507 No abstract available.

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