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Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain.
Xu E, Boddu R, Abdelmotilib HA, Sokratian A, Kelly K, Liu Z, Bryant N, Chandra S, Carlisle SM, Lefkowitz EJ, Harms AS, Benveniste EN, Yacoubian TA, Volpicelli-Daley LA, Standaert DG, West AB. Xu E, et al. Among authors: volpicelli daley la. Mol Neurodegener. 2022 Jan 10;17(1):7. doi: 10.1186/s13024-021-00509-5. Mol Neurodegener. 2022. PMID: 35012605 Free PMC article.
Unique functional and structural properties of the LRRK2 protein ATP-binding pocket.
Liu Z, Galemmo RA Jr, Fraser KB, Moehle MS, Sen S, Volpicelli-Daley LA, DeLucas LJ, Ross LJ, Valiyaveettil J, Moukha-Chafiq O, Pathak AK, Ananthan S, Kezar H, White EL, Gupta V, Maddry JA, Suto MJ, West AB. Liu Z, et al. J Biol Chem. 2014 Nov 21;289(47):32937-51. doi: 10.1074/jbc.M114.602318. Epub 2014 Sep 16. J Biol Chem. 2014. PMID: 25228699 Free PMC article.
Invisible Killers.
Volpicelli-Daley LA, Standaert DG. Volpicelli-Daley LA, et al. Mov Disord. 2016 Jan;31(1):44. doi: 10.1002/mds.26465. Epub 2016 Jan 9. Mov Disord. 2016. PMID: 26748962 No abstract available.
65 results