Opperman T - Search Results

1

Biomarkers of Castrate Resistance in Prostate Cancer: Androgen Receptor Amplification and T877A Mutation Detection by Multiplex Droplet Digital PCR.

Young FP, Becker TM, Nimir M, Opperman T, Chua W, Balakrishnar B, de Souza P, Ma Y. Young FP, et al. Among authors: opperman t. J Clin Med. 2022 Jan 4;11(1):257. doi: 10.3390/jcm11010257. J Clin Med. 2022. PMID: 35011998 Free PMC article.

2

Detection of AR-V7 in Liquid Biopsies of Castrate Resistant Prostate Cancer Patients: A Comparison of AR-V7 Analysis in Circulating Tumor Cells, Circulating Tumor RNA and Exosomes.

Nimir M, Ma Y, Jeffreys SA, Opperman T, Young F, Khan T, Ding P, Chua W, Balakrishnar B, Cooper A, De Souza P, Becker TM. Nimir M, et al. Among authors: opperman t. Cells. 2019 Jul 8;8(7):688. doi: 10.3390/cells8070688. Cells. 2019. PMID: 31288377 Free PMC article.

3

Cell-Based Assay to Determine Type 3 Secretion System Translocon Assembly in Pseudomonas aeruginosa Using Split Luciferase.

Guo H, Geddes EJ, Opperman TJ, Heuck AP. Guo H, et al. Among authors: opperman tj. ACS Infect Dis. 2023 Dec 8;9(12):2652-2664. doi: 10.1021/acsinfecdis.3c00482. Epub 2023 Nov 18. ACS Infect Dis. 2023. PMID: 37978950

4

Exposure of Escherichia coli to antibiotic-efflux pump inhibitor combinations in a pharmacokinetic model: impact on bacterial clearance and drug resistance.

MacGowan AP, Attwood MLG, Noel AR, Barber R, Aron Z, Opperman TJ, Grimsey E, Stone J, Ricci V, Piddock LJV. MacGowan AP, et al. Among authors: opperman tj. J Antimicrob Chemother. 2023 Dec 1;78(12):2869-2877. doi: 10.1093/jac/dkad320. J Antimicrob Chemother. 2023. PMID: 37837411

5

Luciferase-Based High-Throughput Screen with Aspergillus fumigatus to Identify Antifungal Small Molecules.

Opperman TJ, Dhingra S, Gutierrez-Perez C, Kwasny SM, Cramer RA. Opperman TJ, et al. Methods Mol Biol. 2023;2658:17-34. doi: 10.1007/978-1-0716-3155-3_2. Methods Mol Biol. 2023. PMID: 37024692

6

Investigating N-arylpyrimidinamine (NAPA) compounds as early-stage inhibitors against human cytomegalovirus.

Parsons AJ, Ophir SI, Gardner TJ, Paredes JC, Stein KR, Kwasny SM, Cardinale SC, Torhan M, Prichard MN, James SH, Atanasoff KE, G-Dayanandan N, Bowlin TL, Opperman TJ, Tortorella D. Parsons AJ, et al. Among authors: opperman tj. Antiviral Res. 2023 Jan;209:105474. doi: 10.1016/j.antiviral.2022.105474. Epub 2022 Nov 26. Antiviral Res. 2023. PMID: 36511318 Free PMC article.

7

Adjunctive therapy for multidrug-resistant bacterial infections: Type III secretion system and efflux inhibitors.

Moir DT, Opperman TJ, Aron ZD, Bowlin TL. Moir DT, et al. Among authors: opperman tj. Drug Discov Today. 2021 Sep;26(9):2173-2181. doi: 10.1016/j.drudis.2021.03.031. Epub 2021 Apr 9. Drug Discov Today. 2021. PMID: 33845218 Review.

8

trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo.

Aron ZD, Mehrani A, Hoffer ED, Connolly KL, Srinivas P, Torhan MC, Alumasa JN, Cabrera M, Hosangadi D, Barbor JS, Cardinale SC, Kwasny SM, Morin LR, Butler MM, Opperman TJ, Bowlin TL, Jerse A, Stagg SM, Dunham CM, Keiler KC. Aron ZD, et al. Among authors: opperman tj. Nat Commun. 2021 Mar 19;12(1):1799. doi: 10.1038/s41467-021-22012-7. Nat Commun. 2021. PMID: 33741965 Free PMC article.

9

Optimization of a Benzothiazole Indolene Scaffold Targeting Bacterial Cell Wall Assembly.

Chauhan J, Yu W, Cardinale S, Opperman TJ, MacKerell AD Jr, Fletcher S, de Leeuw EP. Chauhan J, et al. Among authors: opperman tj. Drug Des Devel Ther. 2020 Feb 10;14:567-574. doi: 10.2147/DDDT.S226313. eCollection 2020. Drug Des Devel Ther. 2020. PMID: 32103898 Free PMC article.

10

Optimization of a small-molecule Lipid II binder.

Chauhan J, Kwasny SM, Fletcher S, Opperman TJ, de Leeuw EPH. Chauhan J, et al. Among authors: opperman tj. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1849-1853. doi: 10.1016/j.bmcl.2019.04.046. Epub 2019 May 17. Bioorg Med Chem Lett. 2019. PMID: 31126852

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