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Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages.
Tran TT, Mathmann CD, Gatica-Andrades M, Rollo RF, Oelker M, Ljungberg JK, Nguyen TTK, Zamoshnikova A, Kummari LK, Wyer OJK, Irvine KM, Melo-Bolívar J, Gross A, Brown D, Mak JYW, Fairlie DP, Hansford KA, Cooper MA, Giri R, Schreiber V, Joseph SR, Simpson F, Barnett TC, Johansson J, Dankers W, Harris J, Wells TJ, Kapetanovic R, Sweet MJ, Latomanski EA, Newton HJ, Guérillot RJR, Hachani A, Stinear TP, Ong SY, Chandran Y, Hartland EL, Kobe B, Stow JL, Sauer-Eriksson AE, Begun J, Kling JC, Blumenthal A. Tran TT, et al. Among authors: kobe b. PLoS Pathog. 2022 Jan 10;18(1):e1010166. doi: 10.1371/journal.ppat.1010166. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35007292 Free PMC article.
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection.
Valkov E, Stamp A, Dimaio F, Baker D, Verstak B, Roversi P, Kellie S, Sweet MJ, Mansell A, Gay NJ, Martin JL, Kobe B. Valkov E, et al. Among authors: kobe b. Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14879-84. doi: 10.1073/pnas.1104780108. Epub 2011 Aug 22. Proc Natl Acad Sci U S A. 2011. PMID: 21873236 Free PMC article.
The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer.
Chen KE, Richards AA, Ariffin JK, Ross IL, Sweet MJ, Kellie S, Kobe B, Martin JL. Chen KE, et al. Among authors: kobe b. Acta Crystallogr D Biol Crystallogr. 2012 Jun;68(Pt 6):637-48. doi: 10.1107/S0907444912006592. Epub 2012 May 17. Acta Crystallogr D Biol Crystallogr. 2012. PMID: 22683786 Free article.
Crystallization and X-ray diffraction analysis of the N-terminal domain of the Toll-like receptor signalling adaptor protein TRIF/TICAM-1.
Ullah MO, Ve T, Dkhar J, Alaidarous M, Ericsson DJ, Sweet MJ, Mansell A, Kobe B. Ullah MO, et al. Among authors: kobe b. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jul;69(Pt 7):766-70. doi: 10.1107/S174430911301419X. Epub 2013 Jun 28. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23832204 Free PMC article.
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB.
Alaidarous M, Ve T, Ullah MO, Valkov E, Mansell A, Schembri MA, Sweet MJ, Kobe B. Alaidarous M, et al. Among authors: kobe b. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Oct;69(Pt 10):1167-70. doi: 10.1107/S1744309113024408. Epub 2013 Sep 28. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 24100574 Free PMC article.
278 results