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Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages.
Tran TT, Mathmann CD, Gatica-Andrades M, Rollo RF, Oelker M, Ljungberg JK, Nguyen TTK, Zamoshnikova A, Kummari LK, Wyer OJK, Irvine KM, Melo-Bolívar J, Gross A, Brown D, Mak JYW, Fairlie DP, Hansford KA, Cooper MA, Giri R, Schreiber V, Joseph SR, Simpson F, Barnett TC, Johansson J, Dankers W, Harris J, Wells TJ, Kapetanovic R, Sweet MJ, Latomanski EA, Newton HJ, Guérillot RJR, Hachani A, Stinear TP, Ong SY, Chandran Y, Hartland EL, Kobe B, Stow JL, Sauer-Eriksson AE, Begun J, Kling JC, Blumenthal A. Tran TT, et al. Among authors: fairlie dp. PLoS Pathog. 2022 Jan 10;18(1):e1010166. doi: 10.1371/journal.ppat.1010166. eCollection 2022 Jan. PLoS Pathog. 2022. PMID: 35007292 Free PMC article.
Histone deacetylase inhibitors in inflammatory disease.
Halili MA, Andrews MR, Sweet MJ, Fairlie DP. Halili MA, et al. Among authors: fairlie dp. Curr Top Med Chem. 2009;9(3):309-19. doi: 10.2174/156802609788085250. Curr Top Med Chem. 2009. PMID: 19355993 Review.
Inhibitors selective for HDAC6 in enzymes and cells.
Gupta PK, Reid RC, Liu L, Lucke AJ, Broomfield SA, Andrews MR, Sweet MJ, Fairlie DP. Gupta PK, et al. Among authors: fairlie dp. Bioorg Med Chem Lett. 2010 Dec 1;20(23):7067-70. doi: 10.1016/j.bmcl.2010.09.100. Epub 2010 Oct 12. Bioorg Med Chem Lett. 2010. PMID: 20947351
Histone deacetylases as regulators of inflammation and immunity.
Shakespear MR, Halili MA, Irvine KM, Fairlie DP, Sweet MJ. Shakespear MR, et al. Among authors: fairlie dp. Trends Immunol. 2011 Jul;32(7):335-43. doi: 10.1016/j.it.2011.04.001. Epub 2011 May 12. Trends Immunol. 2011. PMID: 21570914 Review.
394 results