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Deletion of the nuclear localization sequence and C-terminus of parathyroid hormone-related protein decreases osteogenesis and chondrogenesis but increases adipogenesis and myogenesis in murine bone marrow stromal cells.
Hildreth BE 3rd, Hernon KM, Dirksen WP, Leong J, Supsavhad W, Boyaka PN, Rosol TJ, Toribio RE. Hildreth BE 3rd, et al. Among authors: hernon km. J Tissue Eng. 2015 Oct 12;6:2041731415609298. doi: 10.1177/2041731415609298. eCollection 2015 Jan-Dec. J Tissue Eng. 2015. PMID: 35003616 Free PMC article.
Engraftment and bone mass are enhanced by PTHrP 1-34 in ectopically transplanted vertebrae (vossicle model) and can be non-invasively monitored with bioluminescence and fluorescence imaging.
Hildreth BE 3rd, Williams MM, Dembek KA, Hernon KM, Rosol TJ, Toribio RE. Hildreth BE 3rd, et al. Among authors: hernon km. Transgenic Res. 2015 Dec;24(6):955-69. doi: 10.1007/s11248-015-9901-9. Epub 2015 Aug 14. Transgenic Res. 2015. PMID: 26271486 Free PMC article.