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Involvement of Multiple Variants of Soluble CD146 in Systemic Sclerosis: Identification of a Novel Profibrotic Factor.
Nollet M, Bachelier R, Joshkon A, Traboulsi W, Mahieux A, Moyon A, Muller A, Somasundaram I, Simoncini S, Peiretti F, Leroyer AS, Guillet B, Granel B, Dignat-George F, Bardin N, Foucault-Bertaud A, Blot-Chabaud M. Nollet M, et al. Among authors: joshkon a. Arthritis Rheumatol. 2022 Jun;74(6):1027-1038. doi: 10.1002/art.42063. Epub 2022 Apr 11. Arthritis Rheumatol. 2022. PMID: 35001552
Therapeutic targeting of soluble CD146/MCAM with the M2J-1 monoclonal antibody prevents metastasis development and procoagulant activity in CD146-positive invasive tumors.
Stalin J, Traboulsi W, Vivancos-Stalin L, Nollet M, Joshkon A, Bachelier R, Guillet B, Lacroix R, Foucault-Bertaud A, Leroyer AS, Dignat-George F, Bardin N, Blot-Chabaud M. Stalin J, et al. Among authors: joshkon a. Int J Cancer. 2020 Sep 15;147(6):1666-1679. doi: 10.1002/ijc.32909. Epub 2020 Feb 22. Int J Cancer. 2020. PMID: 32022257 Free article.
Soluble CD146 is increased in preeclampsia and interacts with galectin-1 to regulate trophoblast migration through VEGFR2 receptor.
Bouvier S, Traboulsi W, Blois SM, Demattei C, Joshkon A, Mousty E, Nollet M, Paulmyer-Lacroix O, Foucault-Bertaud A, Fortier M, Leroyer AS, Bachelier R, Letouzey V, Alfaidy N, Dignat-George F, Blot-Chabaud M, Gris JC, Bardin N. Bouvier S, et al. Among authors: joshkon a. F S Sci. 2022 Feb;3(1):84-94. doi: 10.1016/j.xfss.2021.11.002. Epub 2021 Nov 19. F S Sci. 2022. PMID: 35559998
CD146 at the Interface between Oxidative Stress and the Wnt Signaling Pathway in Systemic Sclerosis.
Heim X, Bermudez J, Joshkon A, Kaspi E, Bachelier R, Nollet M, Vélier M, Dou L, Brodovitch A, Foucault-Bertaud A, Leroyer AS, Benyamine A, Daumas A, Granel B, Sabatier F, Dignat-George F, Blot-Chabaud M, Bardin N. Heim X, et al. Among authors: joshkon a. J Invest Dermatol. 2022 Dec;142(12):3200-3210.e5. doi: 10.1016/j.jid.2022.03.038. Epub 2022 Jun 9. J Invest Dermatol. 2022. PMID: 35690141 Free article.
Endothelial-Specific Deletion of CD146 Protects Against Experimental Glomerulonephritis in Mice.
Abed A, Leroyer AS, Kavvadas P, Authier F, Bachelier R, Foucault-Bertaud A, Bardin N, Cohen CD, Lindenmeyer MT, Genest M, Joshkon A, Jourde-Chiche N, Burtey S, Blot-Chabaud M, Dignat-George F, Chadjichristos CE. Abed A, et al. Among authors: joshkon a. Hypertension. 2021 Apr;77(4):1260-1272. doi: 10.1161/HYPERTENSIONAHA.119.14176. Epub 2021 Mar 10. Hypertension. 2021. PMID: 33689459 Free article.
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