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Loss of p19Arf promotes fibroblast survival during leucine deprivation.
Roby KC, Lieberman A, Kim BJ, Rodríguez NZ, Posimo JM, Tsang T, Verginadis II, Puré E, Brady DC, Koumenis C, Ryeom S. Roby KC, et al. Among authors: pure e. Biol Open. 2022 Feb 15;11(2):bio058728. doi: 10.1242/bio.058728. Epub 2022 Feb 17. Biol Open. 2022. PMID: 34994382 Free PMC article.
Inactivation of Interferon Receptor Promotes the Establishment of Immune Privileged Tumor Microenvironment.
Katlinski KV, Gui J, Katlinskaya YV, Ortiz A, Chakraborty R, Bhattacharya S, Carbone CJ, Beiting DP, Girondo MA, Peck AR, Puré E, Chatterji P, Rustgi AK, Diehl JA, Koumenis C, Rui H, Fuchs SY. Katlinski KV, et al. Among authors: pure e. Cancer Cell. 2017 Feb 13;31(2):194-207. doi: 10.1016/j.ccell.2017.01.004. Cancer Cell. 2017. PMID: 28196594 Free PMC article.
Deletion of Calcineurin Promotes a Protumorigenic Fibroblast Phenotype.
Lieberman A, Barrett R, Kim J, Zhang KL, Avery D, Monslow J, Kim H, Kim BJ, Puré E, Ryeom S. Lieberman A, et al. Among authors: pure e. Cancer Res. 2019 Aug 1;79(15):3928-3939. doi: 10.1158/0008-5472.CAN-19-0056. Epub 2019 Jun 12. Cancer Res. 2019. PMID: 31189649 Free PMC article.
Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs.
Gui J, Zahedi F, Ortiz A, Cho C, Katlinski KV, Alicea-Torres K, Li J, Todd L, Zhang H, Beiting DP, Sander C, Kirkwood JM, Snow BE, Wakeham AC, Mak TW, Diehl JA, Koumenis C, Ryeom SW, Stanger BZ, Puré E, Gabrilovich DI, Fuchs SY. Gui J, et al. Among authors: pure e. Nat Cancer. 2020 Jun;1(6):603-619. doi: 10.1038/s43018-020-0064-0. Epub 2020 May 25. Nat Cancer. 2020. PMID: 34124690 Free PMC article.
A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression.
Verginadis II, Avgousti H, Monslow J, Skoufos G, Chinga F, Kim K, Leli NM, Karagounis IV, Bell BI, Velalopoulou A, Salinas CS, Wu VS, Li Y, Ye J, Scott DA, Osterman AL, Sengupta A, Weljie A, Huang M, Zhang D, Fan Y, Radaelli E, Tobias JW, Rambow F, Karras P, Marine JC, Xu X, Hatzigeorgiou AG, Ryeom S, Diehl JA, Fuchs SY, Puré E, Koumenis C. Verginadis II, et al. Among authors: pure e. Nat Cell Biol. 2022 Jun;24(6):940-953. doi: 10.1038/s41556-022-00918-8. Epub 2022 Jun 2. Nat Cell Biol. 2022. PMID: 35654839 Free PMC article.
Hyaluronan and CD44 antagonize mitogen-dependent cyclin D1 expression in mesenchymal cells.
Kothapalli D, Zhao L, Hawthorne EA, Cheng Y, Lee E, Puré E, Assoian RK. Kothapalli D, et al. Among authors: pure e. J Cell Biol. 2007 Feb 12;176(4):535-44. doi: 10.1083/jcb.200611058. J Cell Biol. 2007. PMID: 17296798 Free PMC article.
Zhang, R. Belkin, C. Yeh, A. Secreto, R.K. Assoian, D.J. Rader, and E. Pure. 2001. J. Clin. Invest. 108:1031-1040); we now characterize the underlying molecular mechanism and document its relevance in vivo. ...
Zhang, R. Belkin, C. Yeh, A. Secreto, R.K. Assoian, D.J. Rader, and E. Pure. 2001. J. Clin. Invest. 108:1031-1040); we now cha …
Loss of cells expressing fibroblast activation protein has variable effects in models of TGF-β and chronic bleomycin-induced fibrosis.
Kimura T, Monslow J, Klampatsa A, Leibowitz M, Sun J, Liousia M, Woodruff P, Moon E, Todd L, Puré E, Albelda SM. Kimura T, et al. Among authors: pure e. Am J Physiol Lung Cell Mol Physiol. 2019 Aug 1;317(2):L271-L282. doi: 10.1152/ajplung.00071.2019. Epub 2019 Jun 12. Am J Physiol Lung Cell Mol Physiol. 2019. PMID: 31188013 Free article.
Fibroblast activation protein (FAP), a cell surface serine protease, is upregulated on a subset of activated fibroblasts (often distinct from alpha-smooth muscle actin-expressing myofibroblasts) associated with matrix remodeling, including fibroblasts in idiopathic pulmonary fibr …
Fibroblast activation protein (FAP), a cell surface serine protease, is upregulated on a subset of activated fibroblasts (often distinct fro …
176 results