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Loss of p19Arf promotes fibroblast survival during leucine deprivation.
Roby KC, Lieberman A, Kim BJ, Rodríguez NZ, Posimo JM, Tsang T, Verginadis II, Puré E, Brady DC, Koumenis C, Ryeom S. Roby KC, et al. Among authors: brady dc. Biol Open. 2022 Feb 15;11(2):bio058728. doi: 10.1242/bio.058728. Epub 2022 Feb 17. Biol Open. 2022. PMID: 34994382 Free PMC article.
CDK7 Inhibition Suppresses Castration-Resistant Prostate Cancer through MED1 Inactivation.
Rasool RU, Natesan R, Deng Q, Aras S, Lal P, Sander Effron S, Mitchell-Velasquez E, Posimo JM, Carskadon S, Baca SC, Pomerantz MM, Siddiqui J, Schwartz LE, Lee DJ, Palanisamy N, Narla G, Den RB, Freedman ML, Brady DC, Asangani IA. Rasool RU, et al. Among authors: brady dc. Cancer Discov. 2019 Nov;9(11):1538-1555. doi: 10.1158/2159-8290.CD-19-0189. Epub 2019 Aug 29. Cancer Discov. 2019. PMID: 31466944 Free PMC article.
Copper biology.
Tsang T, Davis CI, Brady DC. Tsang T, et al. Among authors: brady dc. Curr Biol. 2021 May 10;31(9):R421-R427. doi: 10.1016/j.cub.2021.03.054. Curr Biol. 2021. PMID: 33974864 Free article. Review.
The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation.
Grasso M, Bond GJ, Kim YJ, Boyd S, Matson Dzebo M, Valenzuela S, Tsang T, Schibrowsky NA, Alwan KB, Blackburn NJ, Burslem GM, Wittung-Stafshede P, Winkler DD, Marmorstein R, Brady DC. Grasso M, et al. Among authors: brady dc. J Biol Chem. 2021 Dec;297(6):101314. doi: 10.1016/j.jbc.2021.101314. Epub 2021 Oct 27. J Biol Chem. 2021. PMID: 34715128 Free PMC article.
Copper Modulates the Catalytic Activity of Protein Kinase CK2.
Chojnowski JE, Li R, Tsang T, Alfaran FH, Dick A, Cocklin S, Brady DC, Strochlic TI. Chojnowski JE, et al. Among authors: brady dc. Front Mol Biosci. 2022 Jun 9;9:878652. doi: 10.3389/fmolb.2022.878652. eCollection 2022. Front Mol Biosci. 2022. PMID: 35755824 Free PMC article.
54 results