Zhou HB - Search Results

1

Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment.

Liang JJ, Yu WL, Yang L, Xie BH, Qin KM, Yin YP, Yan JJ, Gong S, Liu TY, Zhou HB, Hong K. Liang JJ, et al. Among authors: zhou hb. Eur J Med Chem. 2022 Feb 5;229:114081. doi: 10.1016/j.ejmech.2021.114081. Epub 2021 Dec 29. Eur J Med Chem. 2022. PMID: 34992039

2

Identification and structure-activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo[2.2.1]hept-2-ene-7-oxide.

Wang P, Min J, Nwachukwu JC, Cavett V, Carlson KE, Guo P, Zhu M, Zheng Y, Dong C, Katzenellenbogen JA, Nettles KW, Zhou HB. Wang P, et al. Among authors: zhou hb. J Med Chem. 2012 Mar 8;55(5):2324-41. doi: 10.1021/jm201556r. Epub 2012 Feb 21. J Med Chem. 2012. PMID: 22283328 Free PMC article.

3

Discovery of novel SERMs with a ferrocenyl entity based on the oxabicyclo[2.2.1]heptene scaffold and evaluation of their antiproliferative effects in breast cancer cells.

Zheng Y, Wang C, Li C, Qiao J, Zhang F, Huang M, Ren W, Dong C, Huang J, Zhou HB. Zheng Y, et al. Among authors: zhou hb. Org Biomol Chem. 2012 Dec 28;10(48):9689-99. doi: 10.1039/c2ob26226f. Epub 2012 Nov 14. Org Biomol Chem. 2012. PMID: 23149805

4

Thiophene-core estrogen receptor ligands having superagonist activity.

Min J, Wang P, Srinivasan S, Nwachukwu JC, Guo P, Huang M, Carlson KE, Katzenellenbogen JA, Nettles KW, Zhou HB. Min J, et al. Among authors: zhou hb. J Med Chem. 2013 Apr 25;56(8):3346-66. doi: 10.1021/jm400157e. Epub 2013 Apr 15. J Med Chem. 2013. PMID: 23586645 Free PMC article.

5

Design, synthesis and biological evaluation of novel estrogen-derived steroid metal complexes.

Zhang X, Zuo Z, Tang J, Wang K, Wang C, Chen W, Li C, Xu W, Xiong X, Yuntai K, Huang J, Lan X, Zhou HB. Zhang X, et al. Among authors: zhou hb. Bioorg Med Chem Lett. 2013 Jul 1;23(13):3793-7. doi: 10.1016/j.bmcl.2013.04.088. Epub 2013 May 9. Bioorg Med Chem Lett. 2013. PMID: 23726343

6

Triaryl-substituted Schiff bases are high-affinity subtype-selective ligands for the estrogen receptor.

Liao ZQ, Dong C, Carlson KE, Srinivasan S, Nwachukwu JC, Chesnut RW, Sharma A, Nettles KW, Katzenellenbogen JA, Zhou HB. Liao ZQ, et al. Among authors: zhou hb. J Med Chem. 2014 Apr 24;57(8):3532-45. doi: 10.1021/jm500268j. Epub 2014 Apr 7. J Med Chem. 2014. PMID: 24708493 Free PMC article.

7

Novel Bioactive Hybrid Compound Dual Targeting Estrogen Receptor and Histone Deacetylase for the Treatment of Breast Cancer.

Tang C, Li C, Zhang S, Hu Z, Wu J, Dong C, Huang J, Zhou HB. Tang C, et al. Among authors: zhou hb. J Med Chem. 2015 Jun 11;58(11):4550-72. doi: 10.1021/acs.jmedchem.5b00099. Epub 2015 Jun 2. J Med Chem. 2015. PMID: 25993269

8

Identification and Structure-Activity Relationships of Diarylhydrazides as Novel Potent and Selective Human Enterovirus Inhibitors.

Han X, Sun N, Wu H, Guo D, Tien P, Dong C, Wu S, Zhou HB. Han X, et al. Among authors: zhou hb. J Med Chem. 2016 Mar 10;59(5):2139-50. doi: 10.1021/acs.jmedchem.5b01803. Epub 2016 Feb 25. J Med Chem. 2016. PMID: 26885567

9

Predictive features of ligand-specific signaling through the estrogen receptor.

Nwachukwu JC, Srinivasan S, Zheng Y, Wang S, Min J, Dong C, Liao Z, Nowak J, Wright NJ, Houtman R, Carlson KE, Josan JS, Elemento O, Katzenellenbogen JA, Zhou HB, Nettles KW. Nwachukwu JC, et al. Among authors: zhou hb. Mol Syst Biol. 2016 Apr 22;12(4):864. doi: 10.15252/msb.20156701. Mol Syst Biol. 2016. PMID: 27107013 Free PMC article.

10

Synthesis and structure-activity relationships of novel hybrid ferrocenyl compounds based on a bicyclic core skeleton for breast cancer therapy.

Li C, Tang C, Hu Z, Zhao C, Li C, Zhang S, Dong C, Zhou HB, Huang J. Li C, et al. Among authors: zhou hb. Bioorg Med Chem. 2016 Jul 1;24(13):3062-3074. doi: 10.1016/j.bmc.2016.05.019. Epub 2016 May 18. Bioorg Med Chem. 2016. PMID: 27240467

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