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Page 1
Identifying differential regulatory control of APOE ɛ4 on African versus European haplotypes as potential therapeutic targets.
Nuytemans K, Lipkin Vasquez M, Wang L, Van Booven D, Griswold AJ, Rajabli F, Celis K, Oron O, Hofmann N, Rolati S, Garcia-Serje C, Zhang S, Jin F, Argenziano M, Grant SFA, Chesi A, Brown CD, Young JI, Dykxhoorn DM, Pericak-Vance MA, Vance JM. Nuytemans K, et al. Among authors: dykxhoorn dm. Alzheimers Dement. 2022 Oct;18(10):1930-1942. doi: 10.1002/alz.12534. Epub 2022 Jan 3. Alzheimers Dement. 2022. PMID: 34978147 Free PMC article.
Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgrounds.
Griswold AJ, Celis K, Bussies PL, Rajabli F, Whitehead PL, Hamilton-Nelson KL, Beecham GW, Dykxhoorn DM, Nuytemans K, Wang L, Gardner OK, Dorfsman DA, Bigio EH, Mesulam MM, Weintraub S, Geula C, Gearing M, McGrath-Martinez E, Dalgard CL, Scott WK, Haines JL, Pericak-Vance MA, Young JI, Vance JM. Griswold AJ, et al. Among authors: dykxhoorn dm. Alzheimers Dement. 2021 Jul;17(7):1179-1188. doi: 10.1002/alz.12287. Epub 2021 Feb 1. Alzheimers Dement. 2021. PMID: 33522086 Free PMC article.
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[No authors listed] [No authors listed] PMID: 35108843
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A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer's Disease in African Ancestry.
Rajabli F, Beecham GW, Hendrie HC, Baiyewu O, Ogunniyi A, Gao S, Kushch NA, Lipkin-Vasquez M, Hamilton-Nelson KL, Young JI, Dykxhoorn DM, Nuytemans K, Kunkle BW, Wang L, Jin F, Liu X, Feliciano-Astacio BE; Alzheimer’s Disease Sequencing Project, Alzheimer’s Disease Genetic Consortium; Schellenberg GD, Dalgard CL, Griswold AJ, Byrd GS, Reitz C, Cuccaro ML, Haines JL, Pericak-Vance MA, Vance JM. Rajabli F, et al. Among authors: dykxhoorn dm. PLoS Genet. 2022 Jul 5;18(7):e1009977. doi: 10.1371/journal.pgen.1009977. eCollection 2022 Jul. PLoS Genet. 2022. PMID: 35788729 Free PMC article.
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[No authors listed] [No authors listed] PMID: 35109225
ABCA7 frameshift deletion associated with Alzheimer disease in African Americans.
Cukier HN, Kunkle BW, Vardarajan BN, Rolati S, Hamilton-Nelson KL, Kohli MA, Whitehead PL, Dombroski BA, Van Booven D, Lang R, Dykxhoorn DM, Farrer LA, Cuccaro ML, Vance JM, Gilbert JR, Beecham GW, Martin ER, Carney RM, Mayeux R, Schellenberg GD, Byrd GS, Haines JL, Pericak-Vance MA; Alzheimer's Disease Genetics Consortium. Cukier HN, et al. Among authors: dykxhoorn dm. Neurol Genet. 2016 May 17;2(3):e79. doi: 10.1212/NXG.0000000000000079. eCollection 2016 Jun. Neurol Genet. 2016. PMID: 27231719 Free PMC article.
101 results