Placental growth factor negatively regulates retinal endothelial cell barrier function through suppression of glucose-6-phosphate dehydrogenase and antioxidant defense systems.
Huang H, Lennikov A, Saddala MS, Gozal D, Grab DJ, Khalyfa A, Fan L.
Huang H, et al. Among authors: lennikov a.
FASEB J. 2019 Dec;33(12):13695-13709. doi: 10.1096/fj.201901353R. Epub 2019 Oct 4.
FASEB J. 2019.
PMID: 31585507
Free PMC article.
The PRDX6 played dual roles in EC barrier function through glutathione peroxidase and phospholipase A(2) activity. In sum, PlGF negatively regulates EC barrier function through the activation of VEGFR1 and VEGFR2 and the suppression of the G6PD/PPP and the antioxidant path …
The PRDX6 played dual roles in EC barrier function through glutathione peroxidase and phospholipase A(2) activity. In sum, PlGF negat …