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Integrated genomic analysis of survival outliers in glioblastoma.
Peng S, Dhruv H, Armstrong B, Salhia B, Legendre C, Kiefer J, Parks J, Virk S, Sloan AE, Ostrom QT, Barnholtz-Sloan JS, Tran NL, Berens ME. Peng S, et al. Neuro Oncol. 2017 Jun 1;19(6):833-844. doi: 10.1093/neuonc/now269. Neuro Oncol. 2017. PMID: 27932423 Free PMC article.
Females have the survival advantage in glioblastoma.
Ostrom QT, Rubin JB, Lathia JD, Berens ME, Barnholtz-Sloan JS. Ostrom QT, et al. Neuro Oncol. 2018 Mar 27;20(4):576-577. doi: 10.1093/neuonc/noy002. Neuro Oncol. 2018. PMID: 29474647 Free PMC article. No abstract available.
Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21.
Ostrom QT, Kinnersley B, Wrensch MR, Eckel-Passow JE, Armstrong G, Rice T, Chen Y, Wiencke JK, McCoy LS, Hansen HM, Amos CI, Bernstein JL, Claus EB, Il'yasova D, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Rubin JB, Lathia JD, Berens ME, Andersson U, Rajaraman P, Chanock SJ, Linet MS, Wang Z, Yeager M; GliomaScan consortium; Houlston RS, Jenkins RB, Melin B, Bondy ML, Barnholtz-Sloan JS. Ostrom QT, et al. Sci Rep. 2018 May 9;8(1):7352. doi: 10.1038/s41598-018-24580-z. Sci Rep. 2018. PMID: 29743610 Free PMC article.
Sex-specific gene and pathway modeling of inherited glioma risk.
Ostrom QT, Coleman W, Huang W, Rubin JB, Lathia JD, Berens ME, Speyer G, Liao P, Wrensch MR, Eckel-Passow JE, Armstrong G, Rice T, Wiencke JK, McCoy LS, Hansen HM, Amos CI, Bernstein JL, Claus EB, Houlston RS, Il'yasova D, Jenkins RB, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Andersson U, Rajaraman P, Chanock SJ, Linet MS, Wang Z, Yeager M; GliomaScan consortium; Melin B, Bondy ML, Barnholtz-Sloan JS. Ostrom QT, et al. Neuro Oncol. 2019 Jan 1;21(1):71-82. doi: 10.1093/neuonc/noy135. Neuro Oncol. 2019. PMID: 30124908 Free PMC article.
Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.
Ostrom QT, Kinnersley B, Armstrong G, Rice T, Chen Y, Wiencke JK, McCoy LS, Hansen HM, Amos CI, Bernstein JL, Claus EB, Eckel-Passow JE, Il'yasova D, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Rubin JB, Andersson U, Rajaraman P, Chanock SJ, Linet MS, Wang Z, Yeager M; GliomaScan consortium; Houlston RS, Jenkins RB, Wrensch MR, Melin B, Bondy ML, Barnholtz-Sloan JS. Ostrom QT, et al. Int J Cancer. 2018 Nov 15;143(10):2359-2366. doi: 10.1002/ijc.31759. Epub 2018 Sep 19. Int J Cancer. 2018. PMID: 30152087 Free PMC article.
Sex is an important prognostic factor for glioblastoma but not for nonglioblastoma.
Gittleman H, Ostrom QT, Stetson LC, Waite K, Hodges TR, Wright CH, Wright J, Rubin JB, Berens ME, Lathia J, Connor JR, Kruchko C, Sloan AE, Barnholtz-Sloan JS. Gittleman H, et al. Neurooncol Pract. 2019 Dec;6(6):451-462. doi: 10.1093/nop/npz019. Epub 2019 May 18. Neurooncol Pract. 2019. PMID: 31832215 Free PMC article.
397 results