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A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling.
Bercu J, Masuda-Herrera MJ, Trejo-Martin A, Hasselgren C, Lord J, Graham J, Schmitz M, Milchak L, Owens C, Lal SH, Robinson RM, Whalley S, Bellion P, Vuorinen A, Gromek K, Hawkins WA, van de Gevel I, Vriens K, Kemper R, Naven R, Ferrer P, Myatt GJ. Bercu J, et al. Regul Toxicol Pharmacol. 2021 Mar;120:104843. doi: 10.1016/j.yrtph.2020.104843. Epub 2020 Dec 17. Regul Toxicol Pharmacol. 2021. PMID: 33340644 Free PMC article.
Corrigendum to a cross-industry collaboration to assess if acute toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling. Regulatory toxicology and pharmacology (2021) 104843.
Bercu J, Masuda Herrera MJ, Trejo-Martin A, Hasselgren C, Lord J, Graham J, Schmitz M, Milchak L, Owens C, Lal SH, Robinson RM, Whalley S, Bellion P, Vuorinen A, Gromek K, Hawkins WA, Van de Gevel I, Vriens K, Kemper R, Naven R, Ferrer P, Myatt GJ. Bercu J, et al. Regul Toxicol Pharmacol. 2022 Jun;131:105165. doi: 10.1016/j.yrtph.2022.105165. Epub 2022 Apr 23. Regul Toxicol Pharmacol. 2022. PMID: 35474000 Free PMC article. No abstract available.
Comparison of permitted daily exposure (PDE) values for active pharmaceutical ingredients (APIs) - Evidence of a robust approach.
Sehner C, Bernier T, Blum K, Clemann N, Glogovac M, Hawkins WA, Kohan M, Linker F, Lovsin-Barle E, Osadolor O, Pfister T, Schulze E, Schwind M, Tuschl G, Wiesner L. Sehner C, et al. Among authors: hawkins wa. Regul Toxicol Pharmacol. 2024 May 21;150:105649. doi: 10.1016/j.yrtph.2024.105649. Online ahead of print. Regul Toxicol Pharmacol. 2024. PMID: 38782234
Combined KRAS-MAPK pathway inhibitors and HER2-directed drug conjugate is efficacious in pancreatic cancer.
Bulle A, Liu P, Seehra K, Bansod S, Chen Y, Zahra K, Somani V, Khawar IA, Chen HP, Dodhiawala PB, Li L, Geng Y, Mo CK, Mahsl J, Ding L, Govindan R, Davies S, Mudd J, Hawkins WG, Fields RC, DeNardo DG, Knoerzer D, Held JM, Grierson PM, Wang-Gillam A, Ruzinova MB, Lim KH. Bulle A, et al. Among authors: hawkins wg. Nat Commun. 2024 Mar 20;15(1):2503. doi: 10.1038/s41467-024-46811-w. Nat Commun. 2024. PMID: 38509064 Free PMC article.
Intratumoral T-cell receptor repertoire composition predicts overall survival in patients with pancreatic ductal adenocarcinoma.
Pothuri VS, Hogg GD, Conant L, Borcherding N, James CA, Mudd J, Williams G, Seo YD, Hawkins WG, Pillarisetty VG, DeNardo DG, Fields RC. Pothuri VS, et al. Among authors: hawkins wg. Oncoimmunology. 2024 Mar 15;13(1):2320411. doi: 10.1080/2162402X.2024.2320411. eCollection 2024. Oncoimmunology. 2024. PMID: 38504847 Free PMC article.
608 results