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Mechanisms of ketamine and its metabolites as antidepressants.
Hess EM, Riggs LM, Michaelides M, Gould TD. Hess EM, et al. Among authors: michaelides m. Biochem Pharmacol. 2022 Mar;197:114892. doi: 10.1016/j.bcp.2021.114892. Epub 2021 Dec 27. Biochem Pharmacol. 2022. PMID: 34968492 Free PMC article. Review.
Pharmacological and behavioral divergence of ketamine enantiomers: implications for abuse liability.
Bonaventura J, Lam S, Carlton M, Boehm MA, Gomez JL, Solís O, Sánchez-Soto M, Morris PJ, Fredriksson I, Thomas CJ, Sibley DR, Shaham Y, Zarate CA Jr, Michaelides M. Bonaventura J, et al. Among authors: michaelides m. Mol Psychiatry. 2021 Nov;26(11):6704-6722. doi: 10.1038/s41380-021-01093-2. Epub 2021 Apr 15. Mol Psychiatry. 2021. PMID: 33859356 Free PMC article.
Target deconvolution studies of (2R,6R)-hydroxynorketamine: an elusive search.
Bonaventura J, Gomez JL, Carlton ML, Lam S, Sanchez-Soto M, Morris PJ, Moaddel R, Kang HJ, Zanos P, Gould TD, Thomas CJ, Sibley DR, Zarate CA Jr, Michaelides M. Bonaventura J, et al. Among authors: michaelides m. Mol Psychiatry. 2022 Oct;27(10):4144-4156. doi: 10.1038/s41380-022-01673-w. Epub 2022 Jun 29. Mol Psychiatry. 2022. PMID: 35768639 Free PMC article.
Acute engagement of Gq-mediated signaling in the bed nucleus of the stria terminalis induces anxiety-like behavior.
Mazzone CM, Pati D, Michaelides M, DiBerto J, Fox JH, Tipton G, Anderson C, Duffy K, McKlveen JM, Hardaway JA, Magness ST, Falls WA, Hammack SE, McElligott ZA, Hurd YL, Kash TL. Mazzone CM, et al. Among authors: michaelides m. Mol Psychiatry. 2018 Jan;23(1):143-153. doi: 10.1038/mp.2016.218. Epub 2016 Dec 13. Mol Psychiatry. 2018. PMID: 27956747 Free PMC article.
The show must go on. Reply to "Distinct functions of S-ketamine and R-ketamine in mediating biobehavioral processes of drug dependency: comments on Bonaventura et al" by Insop Shim.
Bonaventura J, Lam S, Carlton M, Boehm M, Gomez JL, Solís O, Sánchez-Soto M, Morris PJ, Fredriksson I, Thomas CJ, Sibley DR, Shaham Y, Zarate CA Jr, Michaelides M. Bonaventura J, et al. Among authors: michaelides m. Mol Psychiatry. 2023 Dec;28(12):4941-4942. doi: 10.1038/s41380-022-01666-9. Epub 2022 Jun 22. Mol Psychiatry. 2023. PMID: 35732692 No abstract available.
Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone.
Levinstein MR, De Oliveira PA, Casajuana-Martin N, Quiroz C, Budinich RC, Rais R, Rea W, Ventriglia EN, Llopart N, Casadó-Anguera V, Moreno E, Walther D, Glatfelter GC, Weinshenker D, Zarate CA Jr, Casadó V, Baumann MH, Pardo L, Ferré S, Michaelides M. Levinstein MR, et al. Among authors: michaelides m. Mol Psychiatry. 2023 Dec 25. doi: 10.1038/s41380-023-02353-z. Online ahead of print. Mol Psychiatry. 2023. PMID: 38145984
668 results