Scocchi M - Search Results

1

Rational Designed Hybrid Peptides Show up to a 6-Fold Increase in Antimicrobial Activity and Demonstrate Different Ultrastructural Changes as the Parental Peptides Measured by BioSAXS.

Hilpert K, Gani J, Rumancev C, Simpson N, Lopez-Perez PM, Garamus VM, von Gundlach AR, Markov P, Scocchi M, Mikut R, Rosenhahn A. Hilpert K, et al. Among authors: scocchi m. Front Pharmacol. 2021 Dec 3;12:769739. doi: 10.3389/fphar.2021.769739. eCollection 2021. Front Pharmacol. 2021. PMID: 34966279 Free PMC article.

2

Proline-Rich Peptides with Improved Antimicrobial Activity against E. coli, K. pneumoniae, and A. baumannii.

Mardirossian M, Sola R, Beckert B, Collis DWP, Di Stasi A, Armas F, Hilpert K, Wilson DN, Scocchi M. Mardirossian M, et al. Among authors: scocchi m. ChemMedChem. 2019 Dec 17;14(24):2025-2033. doi: 10.1002/cmdc.201900465. Epub 2019 Nov 14. ChemMedChem. 2019. PMID: 31692278 Free PMC article.

3

Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens.

Mardirossian M, Sola R, Beckert B, Valencic E, Collis DWP, Borišek J, Armas F, Di Stasi A, Buchmann J, Syroegin EA, Polikanov YS, Magistrato A, Hilpert K, Wilson DN, Scocchi M. Mardirossian M, et al. Among authors: scocchi m. J Med Chem. 2020 Sep 10;63(17):9590-9602. doi: 10.1021/acs.jmedchem.0c00665. Epub 2020 Aug 13. J Med Chem. 2020. PMID: 32787108 Free article.

4

Characterization of Cetacean Proline-Rich Antimicrobial Peptides Displaying Activity against ESKAPE Pathogens.

Sola R, Mardirossian M, Beckert B, Sanghez De Luna L, Prickett D, Tossi A, Wilson DN, Scocchi M. Sola R, et al. Among authors: scocchi m. Int J Mol Sci. 2020 Oct 6;21(19):7367. doi: 10.3390/ijms21197367. Int J Mol Sci. 2020. PMID: 33036159 Free PMC article.

5

Investigating the mode of action of proline-rich antimicrobial peptides using a genetic approach: a tool to identify new bacterial targets amenable to the design of novel antibiotics.

Scocchi M, Mattiuzzo M, Benincasa M, Antcheva N, Tossi A, Gennaro R. Scocchi M, et al. Methods Mol Biol. 2008;494:161-76. doi: 10.1007/978-1-59745-419-3_9. Methods Mol Biol. 2008. PMID: 18726573

6

Proteolytic activity of Escherichia coli oligopeptidase B against proline-rich antimicrobial peptides.

Mattiuzzo M, De Gobba C, Runti G, Mardirossian M, Bandiera A, Gennaro R, Scocchi M. Mattiuzzo M, et al. Among authors: scocchi m. J Microbiol Biotechnol. 2014 Feb 28;24(2):160-7. doi: 10.4014/jmb.1310.10015. J Microbiol Biotechnol. 2014. PMID: 24225368 Free article.

7

Search for Shorter Portions of the Proline-Rich Antimicrobial Peptide Fragment Bac5(1-25) That Retain Antimicrobial Activity by Blocking Protein Synthesis.

Mardirossian M, Sola R, Degasperi M, Scocchi M. Mardirossian M, et al. Among authors: scocchi m. ChemMedChem. 2019 Feb 5;14(3):343-348. doi: 10.1002/cmdc.201800734. Epub 2019 Jan 17. ChemMedChem. 2019. PMID: 30615305

8

Use of unnatural amino acids to probe structure-activity relationships and mode-of-action of antimicrobial peptides.

Tossi A, Scocchi M, Zahariev S, Gennaro R. Tossi A, et al. Among authors: scocchi m. Methods Mol Biol. 2012;794:169-83. doi: 10.1007/978-1-61779-331-8_10. Methods Mol Biol. 2012. PMID: 21956562

9

Functional characterization of SbmA, a bacterial inner membrane transporter required for importing the antimicrobial peptide Bac7(1-35).

Runti G, Lopez Ruiz Mdel C, Stoilova T, Hussain R, Jennions M, Choudhury HG, Benincasa M, Gennaro R, Beis K, Scocchi M. Runti G, et al. Among authors: scocchi m. J Bacteriol. 2013 Dec;195(23):5343-51. doi: 10.1128/JB.00818-13. Epub 2013 Sep 27. J Bacteriol. 2013. PMID: 24078610 Free PMC article.

10

Effect of size and N-terminal residue characteristics on bacterial cell penetration and antibacterial activity of the proline-rich peptide Bac7.

Guida F, Benincasa M, Zahariev S, Scocchi M, Berti F, Gennaro R, Tossi A. Guida F, et al. Among authors: scocchi m. J Med Chem. 2015 Feb 12;58(3):1195-204. doi: 10.1021/jm501367p. Epub 2015 Jan 14. J Med Chem. 2015. PMID: 25525837 Free article.

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