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The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males.
Croci S, Venneri MA, Mantovani S, Fallerini C, Benetti E, Picchiotti N, Campolo F, Imperatore F, Palmieri M, Daga S, Gabbi C, Montagnani F, Beligni G, Farias TDJ, Carriero ML, Di Sarno L, Alaverdian D, Aslaksen S, Cubellis MV, Spiga O, Baldassarri M, Fava F, Norman PJ, Frullanti E, Isidori AM, Amoroso A, Mari F, Furini S, Mondelli MU, Gen-Covid Multicenter Study, Chiariello M, Renieri A, Meloni I. Croci S, et al. Among authors: cubellis mv. Autophagy. 2022 Jul;18(7):1662-1672. doi: 10.1080/15548627.2021.1995152. Epub 2021 Dec 29. Autophagy. 2022. PMID: 34964709 Free PMC article.
Looking for protein stabilizing drugs with thermal shift assay.
Andreotti G, Monticelli M, Cubellis MV. Andreotti G, et al. Among authors: cubellis mv. Drug Test Anal. 2015 Sep;7(9):831-4. doi: 10.1002/dta.1798. Epub 2015 Apr 5. Drug Test Anal. 2015. PMID: 25845367 Free PMC article.
Taming molecular flexibility to tackle rare diseases.
Cubellis MV, Baaden M, Andreotti G. Cubellis MV, et al. Biochimie. 2015 Jun;113:54-8. doi: 10.1016/j.biochi.2015.03.018. Epub 2015 Apr 2. Biochimie. 2015. PMID: 25841341 Free PMC article.
92 results