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Glucocorticoids coordinate macrophage metabolism through the regulation of the tricarboxylic acid cycle.
Stifel U, Wolfschmitt EM, Vogt J, Wachter U, Vettorazzi S, Tews D, Hogg M, Zink F, Koll NM, Winning S, Mounier R, Chazaud B, Radermacher P, Fischer-Posovszky P, Caratti G, Tuckermann J. Stifel U, et al. Among authors: tuckermann j. Mol Metab. 2022 Mar;57:101424. doi: 10.1016/j.molmet.2021.101424. Epub 2021 Dec 22. Mol Metab. 2022. PMID: 34954109 Free PMC article.
Decreased expression of the glucocorticoid receptor-GILZ pathway in Kupffer cells promotes liver inflammation in obese mice.
Robert O, Boujedidi H, Bigorgne A, Ferrere G, Voican CS, Vettorazzi S, Tuckermann JP, Bouchet-Delbos L, Tran T, Hemon P, Puchois V, Dagher I, Douard R, Gaudin F, Gary-Gouy H, Capel F, Durand-Gasselin I, Prévot S, Rousset S, Naveau S, Godot V, Emilie D, Lombès M, Perlemuter G, Cassard AM. Robert O, et al. J Hepatol. 2016 Apr;64(4):916-24. doi: 10.1016/j.jhep.2015.11.023. Epub 2015 Nov 27. J Hepatol. 2016. PMID: 26639395
Selepressin in Septic Shock: A Step Toward Decatecholaminization?
Asfar P, Russell JA, Tuckermann J, Radermacher P. Asfar P, et al. Among authors: tuckermann j. Crit Care Med. 2016 Jan;44(1):234-6. doi: 10.1097/CCM.0000000000001441. Crit Care Med. 2016. PMID: 26672929 No abstract available.
Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- and HFD-Induced Obesity and Impairs the Feeding-Fasting Transition.
Mueller KM, Hartmann K, Kaltenecker D, Vettorazzi S, Bauer M, Mauser L, Amann S, Jall S, Fischer K, Esterbauer H, Müller TD, Tschöp MH, Magnes C, Haybaeck J, Scherer T, Bordag N, Tuckermann JP, Moriggl R. Mueller KM, et al. Among authors: tuckermann jp. Diabetes. 2017 Feb;66(2):272-286. doi: 10.2337/db16-0381. Epub 2016 Sep 20. Diabetes. 2017. PMID: 27650854
GR-independent down-modulation on GM-CSF bone marrow-derived dendritic cells by the selective glucocorticoid receptor modulator Compound A.
Barcala Tabarrozzi AE, Andreone L, Deckers J, Castro CN, Gimeno ML, Ariolfo L, Berguer PM, Antunica-Noguerol M, Liberman AC, Vettorazzi S, Tuckermann JP, De Bosscher K, Perone MJ. Barcala Tabarrozzi AE, et al. Among authors: tuckermann jp. Sci Rep. 2016 Nov 18;6:36646. doi: 10.1038/srep36646. Sci Rep. 2016. PMID: 27857212 Free PMC article.
The glucocorticoid receptor in monocyte-derived macrophages is critical for cardiac infarct repair and remodeling.
Galuppo P, Vettorazzi S, Hövelmann J, Scholz CJ, Tuckermann JP, Bauersachs J, Fraccarollo D. Galuppo P, et al. Among authors: tuckermann jp. FASEB J. 2017 Nov;31(11):5122-5132. doi: 10.1096/fj.201700317R. Epub 2017 Aug 2. FASEB J. 2017. PMID: 28768721 Free PMC article.
In summary, GR signaling in macrophages, playing a crucial role in tissue-repairing mechanisms, could be a potential therapeutic target during wound healing after ischemic myocardial injury.-Galuppo, P., Vettorazzi, S., Hovelmann, J., Scholz, C.-J., Tuckermann …
In summary, GR signaling in macrophages, playing a crucial role in tissue-repairing mechanisms, could be a potential therapeutic target duri …
188 results