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Chemical and optical control of CRISPR-associated nucleases.
Modell AE, Siriwardena SU, Shoba VM, Li X, Choudhary A. Modell AE, et al. Curr Opin Chem Biol. 2021 Feb;60:113-121. doi: 10.1016/j.cbpa.2020.10.003. Epub 2020 Nov 27. Curr Opin Chem Biol. 2021. PMID: 33253976 Review.
Bifunctional modalities for repurposing protein function.
Modell AE, Lai S, Nguyen TM, Choudhary A. Modell AE, et al. Cell Chem Biol. 2021 Jul 15;28(7):1081-1089. doi: 10.1016/j.chembiol.2021.06.005. Cell Chem Biol. 2021. PMID: 34270935 Free article. Review.
Rational Design of Silicon-Based Zinc Ionophores.
Yamada K, Deb A, Shoba VM, Lim D, Maji B, Modell AE, Choudhary A. Yamada K, et al. Among authors: modell ae. Angew Chem Int Ed Engl. 2022 Jun 7;61(23):e202201698. doi: 10.1002/anie.202201698. Epub 2022 Apr 6. Angew Chem Int Ed Engl. 2022. PMID: 35385189 Free PMC article.
Systematic Targeting of Protein-Protein Interactions.
Modell AE, Blosser SL, Arora PS. Modell AE, et al. Trends Pharmacol Sci. 2016 Aug;37(8):702-713. doi: 10.1016/j.tips.2016.05.008. Epub 2016 Jun 4. Trends Pharmacol Sci. 2016. PMID: 27267699 Free PMC article. Review.
Emerging diabetes therapies: Bringing back the β-cells.
Basile G, Qadir MMF, Mauvais-Jarvis F, Vetere A, Shoba V, Modell AE, Pastori RL, Russ HA, Wagner BK, Dominguez-Bendala J. Basile G, et al. Among authors: modell ae. Mol Metab. 2022 Jun;60:101477. doi: 10.1016/j.molmet.2022.101477. Epub 2022 Mar 21. Mol Metab. 2022. PMID: 35331962 Free PMC article. Review.
Targeting Unoccupied Surfaces on Protein-Protein Interfaces.
Rooklin D, Modell AE, Li H, Berdan V, Arora PS, Zhang Y. Rooklin D, et al. Among authors: modell ae. J Am Chem Soc. 2017 Nov 8;139(44):15560-15563. doi: 10.1021/jacs.7b05960. Epub 2017 Aug 4. J Am Chem Soc. 2017. PMID: 28759230 Free PMC article.