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Development of an Acrylate Derivative Targeting the NLRP3 Inflammasome for the Treatment of Inflammatory Bowel Disease.
Cocco M, Pellegrini C, Martínez-Banaclocha H, Giorgis M, Marini E, Costale A, Miglio G, Fornai M, Antonioli L, López-Castejón G, Tapia-Abellán A, Angosto D, Hafner-Bratkovič I, Regazzoni L, Blandizzi C, Pelegrín P, Bertinaria M. Cocco M, et al. Among authors: bertinaria m. J Med Chem. 2017 May 11;60(9):3656-3671. doi: 10.1021/acs.jmedchem.6b01624. Epub 2017 Apr 24. J Med Chem. 2017. PMID: 28410442
A Comparative Study on the Efficacy of NLRP3 Inflammasome Signaling Inhibitors in a Pre-clinical Model of Bowel Inflammation.
Pellegrini C, Fornai M, Colucci R, Benvenuti L, D’Antongiovanni V, Natale G, Fulceri F, Giorgis M, Marini E, Gastaldi S, Bertinaria M, Blandizzi C, Antonioli L. Pellegrini C, et al. Among authors: bertinaria m. Front Pharmacol. 2018 Dec 3;9:1405. doi: 10.3389/fphar.2018.01405. eCollection 2018. Front Pharmacol. 2018. PMID: 30559669 Free PMC article.
Inflammasome Inhibitors.
Bertinaria M. Bertinaria M. Molecules. 2021 Nov 16;26(22):6912. doi: 10.3390/molecules26226912. Molecules. 2021. PMID: 34834004 Free PMC article.
Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways.
Mastrocola R, Penna C, Tullio F, Femminò S, Nigro D, Chiazza F, Serpe L, Collotta D, Alloatti G, Cocco M, Bertinaria M, Pagliaro P, Aragno M, Collino M. Mastrocola R, et al. Among authors: bertinaria m. Oxid Med Cell Longev. 2016;2016:5271251. doi: 10.1155/2016/5271251. Epub 2016 Dec 8. Oxid Med Cell Longev. 2016. PMID: 28053692 Free PMC article.
A new class of NO-donor H3-antagonists.
Tosco P, Bertinaria M, Di Stilo A, Marini E, Rolando B, Sorba G, Fruttero R, Gasco A. Tosco P, et al. Among authors: bertinaria m. Farmaco. 2004 May;59(5):359-71. doi: 10.1016/j.farmac.2003.12.008. Farmaco. 2004. PMID: 15120315
Amphiphilic NO-donor antioxidants.
Chegaev K, Lazzarato L, Rolando B, Marini E, Lopez GV, Bertinaria M, Di Stilo A, Fruttero R, Gasco A. Chegaev K, et al. Among authors: bertinaria m. ChemMedChem. 2007 Feb;2(2):234-40. doi: 10.1002/cmdc.200600248. ChemMedChem. 2007. PMID: 17183594
45 results