Vilardaga JP - Search Results

1

Precise druggability of the PTH type 1 receptor.

Sutkeviciute I, Lee JY, White AD, Maria CS, Peña KA, Savransky S, Doruker P, Li H, Lei S, Kaynak B, Tu C, Clark LJ, Sanker S, Gardella TJ, Chang W, Bahar I, Vilardaga JP. Sutkeviciute I, et al. Among authors: vilardaga jp. Nat Chem Biol. 2022 Mar;18(3):272-280. doi: 10.1038/s41589-021-00929-w. Epub 2021 Dec 23. Nat Chem Biol. 2022. PMID: 34949836 Free PMC article.

2

Molecular basis of inverse agonism in a G protein-coupled receptor.

Vilardaga JP, Steinmeyer R, Harms GS, Lohse MJ. Vilardaga JP, et al. Nat Chem Biol. 2005 Jun;1(1):25-8. doi: 10.1038/nchembio705. Epub 2005 May 24. Nat Chem Biol. 2005. PMID: 16407989

3

Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor.

Dean T, Vilardaga JP, Potts JT Jr, Gardella TJ. Dean T, et al. Among authors: vilardaga jp. Mol Endocrinol. 2008 Jan;22(1):156-66. doi: 10.1210/me.2007-0274. Epub 2007 Sep 13. Mol Endocrinol. 2008. PMID: 17872377 Free PMC article.

4

Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling.

Vilardaga JP, Nikolaev VO, Lorenz K, Ferrandon S, Zhuang Z, Lohse MJ. Vilardaga JP, et al. Nat Chem Biol. 2008 Feb;4(2):126-31. doi: 10.1038/nchembio.64. Epub 2008 Jan 13. Nat Chem Biol. 2008. PMID: 18193048

5

Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation.

Okazaki M, Ferrandon S, Vilardaga JP, Bouxsein ML, Potts JT Jr, Gardella TJ. Okazaki M, et al. Among authors: vilardaga jp. Proc Natl Acad Sci U S A. 2008 Oct 28;105(43):16525-30. doi: 10.1073/pnas.0808750105. Epub 2008 Oct 22. Proc Natl Acad Sci U S A. 2008. PMID: 18946036 Free PMC article.

6

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.

Ferrandon S, Feinstein TN, Castro M, Wang B, Bouley R, Potts JT, Gardella TJ, Vilardaga JP. Ferrandon S, et al. Among authors: vilardaga jp. Nat Chem Biol. 2009 Oct;5(10):734-42. doi: 10.1038/nchembio.206. Epub 2009 Aug 23. Nat Chem Biol. 2009. PMID: 19701185 Free PMC article.

7

Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm.

Vilardaga JP, Romero G, Friedman PA, Gardella TJ. Vilardaga JP, et al. Cell Mol Life Sci. 2011 Jan;68(1):1-13. doi: 10.1007/s00018-010-0465-9. Epub 2010 Aug 12. Cell Mol Life Sci. 2011. PMID: 20703892 Free PMC article. Review.

8

G-protein-coupled receptor heteromer dynamics.

Vilardaga JP, Agnati LF, Fuxe K, Ciruela F. Vilardaga JP, et al. J Cell Sci. 2010 Dec 15;123(Pt 24):4215-20. doi: 10.1242/jcs.063354. J Cell Sci. 2010. PMID: 21123619 Free PMC article.

9

Retromer terminates the generation of cAMP by internalized PTH receptors.

Feinstein TN, Wehbi VL, Ardura JA, Wheeler DS, Ferrandon S, Gardella TJ, Vilardaga JP. Feinstein TN, et al. Among authors: vilardaga jp. Nat Chem Biol. 2011 May;7(5):278-84. doi: 10.1038/nchembio.545. Epub 2011 Mar 27. Nat Chem Biol. 2011. PMID: 21445058 Free PMC article.

10

Studying ligand efficacy at G protein-coupled receptors using FRET.

Vilardaga JP. Vilardaga JP. Methods Mol Biol. 2011;756:133-48. doi: 10.1007/978-1-61779-160-4_6. Methods Mol Biol. 2011. PMID: 21870223 Free PMC article.

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