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Understanding pneumococcal serotype 1 biology through population genomic analysis.
Chaguza C, Cornick JE, Harris SR, Andam CP, Bricio-Moreno L, Yang M, Yalcin F, Ousmane S, Govindpersad S, Senghore M, Ebruke C, Du Plessis M, Kiran AM, Pluschke G, Sigauque B, McGee L, Klugman KP, Turner P, Corander J, Parkhill J, Collard JM, Antonio M, von Gottberg A, Heyderman RS, French N, Kadioglu A, Hanage WP, Everett DB, Bentley SD; PAGe Consortium. Chaguza C, et al. Among authors: yang m. BMC Infect Dis. 2016 Nov 8;16(1):649. doi: 10.1186/s12879-016-1987-z. BMC Infect Dis. 2016. PMID: 27821148 Free PMC article.
Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism.
Chaguza C, Yang M, Cornick JE, du Plessis M, Gladstone RA, Kwambana-Adams BA, Lo SW, Ebruke C, Tonkin-Hill G, Peno C, Senghore M, Obaro SK, Ousmane S, Pluschke G, Collard JM, Sigaùque B, French N, Klugman KP, Heyderman RS, McGee L, Antonio M, Breiman RF, von Gottberg A, Everett DB, Kadioglu A, Bentley SD. Chaguza C, et al. Among authors: yang m. Commun Biol. 2020 Oct 8;3(1):559. doi: 10.1038/s42003-020-01290-9. Commun Biol. 2020. PMID: 33033372 Free PMC article.
Comparative Genomics of Disease and Carriage Serotype 1 Pneumococci.
Chaguza C, Ebruke C, Senghore M, Lo SW, Tientcheu PE, Gladstone RA, Tonkin-Hill G, Cornick JE, Yang M, Worwui A, McGee L, Breiman RF, Klugman KP, Kadioglu A, Everett DB, Mackenzie G, Croucher NJ, Roca A, Kwambana-Adams BA, Antonio M, Bentley SD. Chaguza C, et al. Among authors: yang m. Genome Biol Evol. 2022 Apr 10;14(4):evac052. doi: 10.1093/gbe/evac052. Genome Biol Evol. 2022. PMID: 35439297 Free PMC article.
Comparative Genomic Analysis and In Vivo Modeling of Streptococcus pneumoniae ST3081 and ST618 Isolates Reveal Key Genetic and Phenotypic Differences Contributing to Clonal Replacement of Serotype 1 in The Gambia.
Bricio-Moreno L, Ebruke C, Chaguza C, Cornick J, Kwambana-Adams B, Yang M, Mackenzie G, Wren BW, Everett D, Antonio M, Kadioglu A. Bricio-Moreno L, et al. Among authors: yang m. J Infect Dis. 2017 Dec 5;216(10):1318-1327. doi: 10.1093/infdis/jix472. J Infect Dis. 2017. PMID: 28968897 Free PMC article.
Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival.
Subramanian K, Neill DR, Malak HA, Spelmink L, Khandaker S, Dalla Libera Marchiori G, Dearing E, Kirby A, Yang M, Achour A, Nilvebrant J, Nygren PÅ, Plant L, Kadioglu A, Henriques-Normark B. Subramanian K, et al. Among authors: yang m. Nat Microbiol. 2019 Jan;4(1):62-70. doi: 10.1038/s41564-018-0280-x. Epub 2018 Nov 12. Nat Microbiol. 2019. PMID: 30420782 Free PMC article.
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