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Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia.
Koskuvi M, Lehtonen Š, Trontti K, Keuters M, Wu YC, Koivisto H, Ludwig A, Plotnikova L, Virtanen PLJ, Räsänen N, Kaipainen S, Hyötyläinen I, Dhungana H, Giniatullina R, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Lähteenvuo M, Tohka J, Giniatullin R, Rivera C, Hovatta I, Tanila H, Tiihonen J, Koistinaho J. Koskuvi M, et al. Among authors: lehtonen s. Glia. 2022 Apr;70(4):650-660. doi: 10.1002/glia.24131. Epub 2021 Dec 22. Glia. 2022. PMID: 34936134 Free PMC article.
Nrf2 regulates neurogenesis and protects neural progenitor cells against Aβ toxicity.
Kärkkäinen V, Pomeshchik Y, Savchenko E, Dhungana H, Kurronen A, Lehtonen S, Naumenko N, Tavi P, Levonen AL, Yamamoto M, Malm T, Magga J, Kanninen KM, Koistinaho J. Kärkkäinen V, et al. Among authors: lehtonen s. Stem Cells. 2014 Jul;32(7):1904-16. doi: 10.1002/stem.1666. Stem Cells. 2014. PMID: 24753106
Transplanted Human Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Do Not Promote Functional Recovery of Pharmacologically Immunosuppressed Mice With Contusion Spinal Cord Injury.
Pomeshchik Y, Puttonen KA, Kidin I, Ruponen M, Lehtonen S, Malm T, Åkesson E, Hovatta O, Koistinaho J. Pomeshchik Y, et al. Among authors: lehtonen s. Cell Transplant. 2015;24(9):1799-812. doi: 10.3727/096368914X684079. Epub 2014 Sep 8. Cell Transplant. 2015. PMID: 25203632 Free article.
Immunomodulation by interleukin-33 is protective in stroke through modulation of inflammation.
Korhonen P, Kanninen KM, Lehtonen Š, Lemarchant S, Puttonen KA, Oksanen M, Dhungana H, Loppi S, Pollari E, Wojciechowski S, Kidin I, García-Berrocoso T, Giralt D, Montaner J, Koistinaho J, Malm T. Korhonen P, et al. Among authors: lehtonen s. Brain Behav Immun. 2015 Oct;49:322-36. doi: 10.1016/j.bbi.2015.06.013. Epub 2015 Jun 22. Brain Behav Immun. 2015. PMID: 26111431
Pyrrolidine dithiocarbamate activates the Nrf2 pathway in astrocytes.
Liddell JR, Lehtonen S, Duncan C, Keksa-Goldsteine V, Levonen AL, Goldsteins G, Malm T, White AR, Koistinaho J, Kanninen KM. Liddell JR, et al. Among authors: lehtonen s. J Neuroinflammation. 2016 Feb 26;13:49. doi: 10.1186/s12974-016-0515-9. J Neuroinflammation. 2016. PMID: 26920699 Free PMC article.
Creation of a library of induced pluripotent stem cells from Parkinsonian patients.
Holmqvist S, Lehtonen Š, Chumarina M, Puttonen KA, Azevedo C, Lebedeva O, Ruponen M, Oksanen M, Djelloul M, Collin A, Goldwurm S, Meyer M, Lagarkova M, Kiselev S, Koistinaho J, Roybon L. Holmqvist S, et al. Among authors: lehtonen s. NPJ Parkinsons Dis. 2016 Jun 2;2:16009. doi: 10.1038/npjparkd.2016.9. eCollection 2016. NPJ Parkinsons Dis. 2016. PMID: 28725696 Free PMC article.
PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease.
Oksanen M, Petersen AJ, Naumenko N, Puttonen K, Lehtonen Š, Gubert Olivé M, Shakirzyanova A, Leskelä S, Sarajärvi T, Viitanen M, Rinne JO, Hiltunen M, Haapasalo A, Giniatullin R, Tavi P, Zhang SC, Kanninen KM, Hämäläinen RH, Koistinaho J. Oksanen M, et al. Among authors: lehtonen s. Stem Cell Reports. 2017 Dec 12;9(6):1885-1897. doi: 10.1016/j.stemcr.2017.10.016. Epub 2017 Nov 16. Stem Cell Reports. 2017. PMID: 29153989 Free PMC article.
224 results