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Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections.
Goss CH, Kaneko Y, Khuu L, Anderson GD, Ravishankar S, Aitken ML, Lechtzin N, Zhou G, Czyz DM, McLean K, Olakanmi O, Shuman HA, Teresi M, Wilhelm E, Caldwell E, Salipante SJ, Hornick DB, Siehnel RJ, Becker L, Britigan BE, Singh PK. Goss CH, et al. Among authors: ravishankar s. Sci Transl Med. 2018 Sep 26;10(460):eaat7520. doi: 10.1126/scitranslmed.aat7520. Sci Transl Med. 2018. PMID: 30257953 Free PMC article. Clinical Trial.
Bacterial fitness in chronic wounds appears to be mediated by the capacity for high-density growth, not virulence or biofilm functions.
Morgan SJ, Lippman SI, Bautista GE, Harrison JJ, Harding CL, Gallagher LA, Cheng AC, Siehnel R, Ravishankar S, Usui ML, Olerud JE, Fleckman P, Wolcott RD, Manoil C, Singh PK. Morgan SJ, et al. Among authors: ravishankar s. PLoS Pathog. 2019 Mar 20;15(3):e1007511. doi: 10.1371/journal.ppat.1007511. eCollection 2019 Mar. PLoS Pathog. 2019. PMID: 30893371 Free PMC article.
Maintenance tobramycin primarily affects untargeted bacteria in the CF sputum microbiome.
Nelson MT, Wolter DJ, Eng A, Weiss EJ, Vo AT, Brittnacher MJ, Hayden HS, Ravishankar S, Bautista G, Ratjen A, Blackledge M, McNamara S, Nay L, Majors C, Miller SI, Borenstein E, Simon RH, LiPuma JJ, Hoffman LR. Nelson MT, et al. Among authors: ravishankar s. Thorax. 2020 Sep;75(9):780-790. doi: 10.1136/thoraxjnl-2019-214187. Epub 2020 Jul 6. Thorax. 2020. PMID: 32631930 Free PMC article.
Geographic EBV variants confound disease-specific variant interpretation and predict variable immune therapy responses.
Briercheck EL, Ravishankar S, Ahmed EH, Carias Alvarado CC, Barrios Menéndez JC, Silva O, Solórzano-Ortiz E, Siliezar Tala MM, Stevenson PA, Xu Y, Wohns AW, Enriquez-Vera D, Barrionuevo C, Yu SC, Freud AG, Weigel C, Oakes CC, Weinstock DM, Klimaszewski HL, Ngankeu A, Mutalima N, Samayoa-Reyes G, Newton R Prof, Rochford R, Valvert F, Natkunam Y, Shustov A, Baiocchi RA, Warren EH. Briercheck EL, et al. Among authors: ravishankar s. Blood Adv. 2024 May 30:bloodadvances.2023012461. doi: 10.1182/bloodadvances.2023012461. Online ahead of print. Blood Adv. 2024. PMID: 38815238
Bacterial diversity and composition on the rinds of specific melon cultivars and hybrids from across different growing regions in the United States.
Goforth M, Obergh V, Park R, Porchas M, Crosby KM, Jifon JL, Ravishankar S, Brierley P, Leskovar DL, Turini TA, Schultheis J, Coolong T, Miller R, Koiwa H, Patil BS, Cooper MA, Huynh S, Parker CT, Guan W, Cooper KK. Goforth M, et al. Among authors: ravishankar s. PLoS One. 2024 Apr 11;19(4):e0293861. doi: 10.1371/journal.pone.0293861. eCollection 2024. PLoS One. 2024. PMID: 38603714 Free PMC article.
Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies.
Nazeen S, Wang X, Zielinski D, Lam I, Hallacli E, Xu P, Ethier E, Strom R, Zanella CA, Nithianandam V, Ritter D, Henderson A, Saurat N, Afroz J, Nutter-Upham A, Benyamini H, Copty J, Ravishankar S, Morrow A, Mitchel J, Neavin D, Gupta R, Farbehi N, Grundman J, Myers RH, Scherzer CR, Trojanowski JQ, Van Deerlin VM, Cooper AA, Lee EB, Erlich Y, Lindquist S, Peng J, Geschwind DH, Powell J, Studer L, Feany MB, Sunyaev SR, Khurana V. Nazeen S, et al. Among authors: ravishankar s. bioRxiv [Preprint]. 2024 Mar 7:2024.03.03.583145. doi: 10.1101/2024.03.03.583145. bioRxiv. 2024. PMID: 38496508 Free PMC article. Preprint.
226 results