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Brain Penetrant, but not Peripherally Restricted, Synthetic Cannabinoid 1 Receptor Agonists Promote Morphine-Mediated Respiratory Depression.
Wiese BM, Liktor-Busa E, Couture SA, Nikas SP, Ji L, Liu Y, Makriyannis A, Spigelman I, Vanderah TW, Largent-Milnes TM. Wiese BM, et al. Among authors: couture sa. Cannabis Cannabinoid Res. 2022 Oct;7(5):621-627. doi: 10.1089/can.2021.0090. Epub 2021 Dec 17. Cannabis Cannabinoid Res. 2022. PMID: 34935460 Free PMC article.
Cannabinoid-2 Agonism with AM2301 Mitigates Morphine-Induced Respiratory Depression.
Wiese BM, Liktor-Busa E, Levine A, Couture SA, Nikas SP, Ji L, Liu Y, Mackie K, Makriyannis A, Largent-Milnes TM, Vanderah TW. Wiese BM, et al. Among authors: couture sa. Cannabis Cannabinoid Res. 2021 Oct;6(5):401-412. doi: 10.1089/can.2020.0076. Epub 2020 Nov 13. Cannabis Cannabinoid Res. 2021. PMID: 33998869 Free PMC article.
Delta/mu opioid receptor interactions in operant conditioning assays of pain-depressed responding and drug-induced rate suppression: assessment of therapeutic index in male Sprague Dawley rats.
Cone K, Lanpher J, Kinens A, Richard P, Couture S, Brackin R, Payne E, Harrington K, Rice KC, Stevenson GW. Cone K, et al. Psychopharmacology (Berl). 2018 May;235(5):1609-1618. doi: 10.1007/s00213-018-4876-x. Epub 2018 Mar 23. Psychopharmacology (Berl). 2018. PMID: 29572653 Free PMC article.