Mangion I - Search Results

1

Enantioselective UHPLC Screening Combined with In Silico Modeling for Streamlined Development of Ultrafast Enantiopurity Assays.

Losacco GL, Wang H, Haidar Ahmad IA, DaSilva J, Makarov AA, Mangion I, Gasparrini F, Lämmerhofer M, Armstrong DW, Regalado EL. Losacco GL, et al. Among authors: mangion i. Anal Chem. 2022 Jan 25;94(3):1804-1812. doi: 10.1021/acs.analchem.1c04585. Epub 2021 Dec 21. Anal Chem. 2022. PMID: 34931812

2

Are fluorine-rich pharmaceuticals lost by partition into fluorous phases?

Sun S, Zawatzky K, Regalado EL, Mangion IK, Welch CJ. Sun S, et al. J Pharm Biomed Anal. 2016 Sep 5;128:106-110. doi: 10.1016/j.jpba.2016.05.025. Epub 2016 May 17. J Pharm Biomed Anal. 2016. PMID: 27239759

3

Visualizing and studying frictional heating effects in reversed-phase liquid chromatography using infrared thermal imaging.

Makarov AA, Mann BF, Regalado EL, Pirrone GF, Sun C, Sun S, Nowak T, Wang H, Mangion I. Makarov AA, et al. Among authors: mangion i. Anal Chim Acta. 2018 Aug 14;1018:1-6. doi: 10.1016/j.aca.2018.02.061. Epub 2018 Mar 9. Anal Chim Acta. 2018. PMID: 29605126

4

Generic anion-exchange chromatography method for analytical and preparative separation of nucleotides in the development and manufacture of drug substances.

Tsay FR, Haidar Ahmad IA, Henderson D, Schiavone N, Liu Z, Makarov AA, Mangion I, Regalado EL. Tsay FR, et al. Among authors: mangion i. J Chromatogr A. 2019 Feb 22;1587:129-135. doi: 10.1016/j.chroma.2018.12.018. Epub 2018 Dec 11. J Chromatogr A. 2019. PMID: 30591245

5

Combination of circular dichroism spectroscopy and size-exclusion chromatography coupled with HDX-MS for studying global conformational structures of peptides in solution.

Schiavone NM, Pirrone GF, Guetschow ED, Mangion I, Makarov AA. Schiavone NM, et al. Among authors: mangion i. Talanta. 2019 Mar 1;194:177-182. doi: 10.1016/j.talanta.2018.09.077. Epub 2018 Sep 25. Talanta. 2019. PMID: 30609519

6

Use of MALDI-MS with solid-state hydrogen deuterium exchange for semi-automated assessment of peptide and protein physical stability in lyophilized solids.

Kabaria SR, Mangion I, Makarov AA, Pirrone GF. Kabaria SR, et al. Among authors: mangion i. Anal Chim Acta. 2019 Apr 25;1054:114-121. doi: 10.1016/j.aca.2018.12.034. Epub 2019 Jan 9. Anal Chim Acta. 2019. PMID: 30712581

7

Evaluation of global conformational changes in peptides and proteins following purification by supercritical fluid chromatography.

Schiavone NM, Bennett R, Hicks MB, Pirrone GF, Regalado EL, Mangion I, Makarov AA. Schiavone NM, et al. Among authors: mangion i. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Mar 15;1110-1111:94-100. doi: 10.1016/j.jchromb.2019.02.012. Epub 2019 Feb 13. J Chromatogr B Analyt Technol Biomed Life Sci. 2019. PMID: 30785083

8

Multi-column ultra-high performance liquid chromatography screening with chaotropic agents and computer-assisted separation modeling enables process development of new drug substances.

Haidar Ahmad IA , Chen W , Halsey HM , Klapars A , Limanto J , Pirrone GF , Nowak T , Bennett R , Hartman R , Makarov AA , Mangion I , Regalado EL . Haidar Ahmad IA , et al. Among authors: mangion i. Analyst. 2019 Apr 23;144(9):2872-2880. doi: 10.1039/c8an02499e. Analyst. 2019. PMID: 30830135

9

The Emergence of Universal Chromatographic Methods in the Research and Development of New Drug Substances.

Regalado EL, Haidar Ahmad IA, Bennett R, D'Atri V, Makarov AA, Humphrey GR, Mangion I, Guillarme D. Regalado EL, et al. Among authors: mangion i. Acc Chem Res. 2019 Jul 16;52(7):1990-2002. doi: 10.1021/acs.accounts.9b00068. Epub 2019 Jun 14. Acc Chem Res. 2019. PMID: 31198042

10

Chaotropic Effects in Sub/Supercritical Fluid Chromatography via Ammonium Hydroxide in Water-Rich Modifiers: Enabling Separation of Peptides and Highly Polar Pharmaceuticals at the Preparative Scale.

Liu J, Makarov AA, Bennett R, Haidar Ahmad IA, DaSilva J, Reibarkh M, Mangion I, Mann BF, Regalado EL. Liu J, et al. Among authors: mangion i. Anal Chem. 2019 Nov 5;91(21):13907-13915. doi: 10.1021/acs.analchem.9b03408. Epub 2019 Oct 8. Anal Chem. 2019. PMID: 31549812

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