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Comparing the preclinical risk profile of inhalable candidate and potential candidate modified risk tobacco products: A bridging use case.
Schlage WK, Titz B, Iskandar A, Poussin C, Van der Toorn M, Wong ET, Pratte P, Maeder S, Schaller JP, Pospisil P, Boue S, Vuillaume G, Leroy P, Martin F, Ivanov NV, Peitsch MC, Hoeng J. Schlage WK, et al. Among authors: van der toorn m. Toxicol Rep. 2020 Sep 12;7:1187-1206. doi: 10.1016/j.toxrep.2020.09.004. eCollection 2020. Toxicol Rep. 2020. PMID: 32995294 Free PMC article.
Pulmonary Delivery of Aerosolized Chloroquine and Hydroxychloroquine to Treat COVID-19: In Vitro Experimentation to Human Dosing Predictions.
Kolli AR, Semren TZ, Bovard D, Majeed S, van der Toorn M, Scheuner S, Guy PA, Kuczaj A, Mazurov A, Frentzel S, Calvino-Martin F, Ivanov NV, O'Mullane J, Peitsch MC, Hoeng J. Kolli AR, et al. Among authors: van der toorn m. AAPS J. 2022 Feb 7;24(1):33. doi: 10.1208/s12248-021-00666-x. AAPS J. 2022. PMID: 35132508 Free PMC article.
In vitro systems toxicology-based assessment of the potential modified risk tobacco product CHTP 1.2 for vascular inflammation- and cytotoxicity-associated mechanisms promoting adhesion of monocytic cells to human coronary arterial endothelial cells.
Poussin C, Laurent A, Kondylis A, Marescotti D, van der Toorn M, Guedj E, Goedertier D, Acali S, Pak C, Dulize R, Baumer K, Peric D, Maluenda E, Bornand D, Suarez IG, Schlage WK, Ivanov NV, Peitsch MC, Hoeng J. Poussin C, et al. Among authors: van der toorn m. Food Chem Toxicol. 2018 Oct;120:390-406. doi: 10.1016/j.fct.2018.07.025. Epub 2018 Jul 17. Food Chem Toxicol. 2018. PMID: 30026091 Free article.
Systems toxicology study reveals reduced impact of heated tobacco product aerosol extract relative to cigarette smoke on premature aging and exacerbation effects in aged aortic cells in vitro.
Poussin C, van der Toorn M, Scheuner S, Piault R, Kondylis A, Savioz R, Dulize R, Peric D, Guedj E, Maranzano F, Merg C, Morelli M, Egesipe AL, Johne S, Majeed S, Pak C, Schneider T, Schlage WK, Ivanov NV, Peitsch MC, Hoeng J. Poussin C, et al. Among authors: van der toorn m. Arch Toxicol. 2021 Oct;95(10):3341-3359. doi: 10.1007/s00204-021-03123-y. Epub 2021 Jul 27. Arch Toxicol. 2021. PMID: 34313809 Free PMC article.
Assessment of mitochondrial function following short- and long-term exposure of human bronchial epithelial cells to total particulate matter from a candidate modified-risk tobacco product and reference cigarettes.
Malinska D, Szymański J, Patalas-Krawczyk P, Michalska B, Wojtala A, Prill M, Partyka M, Drabik K, Walczak J, Sewer A, Johne S, Luettich K, Peitsch MC, Hoeng J, Duszyński J, Szczepanowska J, van der Toorn M, Wieckowski MR. Malinska D, et al. Among authors: van der toorn m. Food Chem Toxicol. 2018 May;115:1-12. doi: 10.1016/j.fct.2018.02.013. Epub 2018 Feb 13. Food Chem Toxicol. 2018. PMID: 29448087 Free article.
40 results