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The length distribution of frangible biofilaments.
Michaels TC, Yde P, Willis JC, Jensen MH, Otzen D, Dobson CM, Buell AK, Knowles TP. Michaels TC, et al. J Chem Phys. 2015 Oct 28;143(16):164901. doi: 10.1063/1.4933230. J Chem Phys. 2015. PMID: 26520548
Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species.
Iljina M, Hong L, Horrocks MH, Ludtmann MH, Choi ML, Hughes CD, Ruggeri FS, Guilliams T, Buell AK, Lee JE, Gandhi S, Lee SF, Bryant CE, Vendruscolo M, Knowles TPJ, Dobson CM, De Genst E, Klenerman D. Iljina M, et al. Among authors: knowles tpj. BMC Biol. 2017 Jul 3;15(1):57. doi: 10.1186/s12915-017-0390-6. BMC Biol. 2017. PMID: 28673288 Free PMC article.
Silk micrococoons for protein stabilisation and molecular encapsulation.
Shimanovich U, Ruggeri FS, De Genst E, Adamcik J, Barros TP, Porter D, Müller T, Mezzenga R, Dobson CM, Vollrath F, Holland C, Knowles TPJ. Shimanovich U, et al. Among authors: knowles tpj. Nat Commun. 2017 Jul 19;8:15902. doi: 10.1038/ncomms15902. Nat Commun. 2017. PMID: 28722016 Free PMC article.
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.
Qamar S, Wang G, Randle SJ, Ruggeri FS, Varela JA, Lin JQ, Phillips EC, Miyashita A, Williams D, Ströhl F, Meadows W, Ferry R, Dardov VJ, Tartaglia GG, Farrer LA, Kaminski Schierle GS, Kaminski CF, Holt CE, Fraser PE, Schmitt-Ulms G, Klenerman D, Knowles T, Vendruscolo M, St George-Hyslop P. Qamar S, et al. Cell. 2018 Apr 19;173(3):720-734.e15. doi: 10.1016/j.cell.2018.03.056. Cell. 2018. PMID: 29677515 Free PMC article.
389 results