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A single-cell atlas of mouse lung development.
Negretti NM, Plosa EJ, Benjamin JT, Schuler BA, Habermann AC, Jetter CS, Gulleman P, Bunn C, Hackett AN, Ransom M, Taylor CJ, Nichols D, Matlock BK, Guttentag SH, Blackwell TS, Banovich NE, Kropski JA, Sucre JMS. Negretti NM, et al. Among authors: hackett an. Development. 2021 Dec 15;148(24):dev199512. doi: 10.1242/dev.199512. Epub 2021 Dec 20. Development. 2021. PMID: 34927678 Free PMC article.
Age-determined expression of priming protease TMPRSS2 and localization of SARS-CoV-2 in lung epithelium.
Schuler BA, Habermann AC, Plosa EJ, Taylor CJ, Jetter C, Negretti NM, Kapp ME, Benjamin JT, Gulleman P, Nichols DS, Braunstein LZ, Hackett A, Koval M, Guttentag SH, Blackwell TS, Webber SA, Banovich NE; Vanderbilt COVID-19 Consortium Cohort; Human Cell Atlas Biological Network; Kropski JA, Sucre JM. Schuler BA, et al. J Clin Invest. 2021 Jan 4;131(1):e140766. doi: 10.1172/JCI140766. J Clin Invest. 2021. PMID: 33180746 Free PMC article.
Age-determined expression of priming protease TMPRSS2 and localization of SARS-CoV-2 infection in the lung epithelium.
Schuler BA, Christian Habermann A, Plosa EJ, Taylor CJ, Jetter C, Kapp ME, Benjamin JT, Gulleman P, Nichols DS, Braunstein LZ, Hackett A, Koval M, Guttentag SH, Blackwell TS; Vanderbilt COVID-19 Consortium Cohort; Webber SA, Banovich NE, Kropski JA, Sucre JMS; HCA Lung Biological Network. Schuler BA, et al. bioRxiv [Preprint]. 2020 Aug 3:2020.05.22.111187. doi: 10.1101/2020.05.22.111187. bioRxiv. 2020. PMID: 32511364 Free PMC article. Updated. Preprint.
Combining Cep290 and Mkks ciliopathy alleles in mice rescues sensory defects and restores ciliogenesis.
Rachel RA, May-Simera HL, Veleri S, Gotoh N, Choi BY, Murga-Zamalloa C, McIntyre JC, Marek J, Lopez I, Hackett AN, Zhang J, Brooks M, den Hollander AI, Beales PL, Li T, Jacobson SG, Sood R, Martens JR, Liu P, Friedman TB, Khanna H, Koenekoop RK, Kelley MW, Swaroop A. Rachel RA, et al. Among authors: hackett an. J Clin Invest. 2012 Apr;122(4):1233-45. doi: 10.1172/JCI60981. Epub 2012 Mar 26. J Clin Invest. 2012. PMID: 22446187 Free PMC article.
CEP290 alleles in mice disrupt tissue-specific cilia biogenesis and recapitulate features of syndromic ciliopathies.
Rachel RA, Yamamoto EA, Dewanjee MK, May-Simera HL, Sergeev YV, Hackett AN, Pohida K, Munasinghe J, Gotoh N, Wickstead B, Fariss RN, Dong L, Li T, Swaroop A. Rachel RA, et al. Among authors: hackett an. Hum Mol Genet. 2015 Jul 1;24(13):3775-91. doi: 10.1093/hmg/ddv123. Epub 2015 Apr 9. Hum Mol Genet. 2015. PMID: 25859007 Free PMC article.