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Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.
Dieckmann S, Strohmeyer A, Willershäuser M, Maurer SF, Wurst W, Marschall S, de Angelis MH, Kühn R, Worthmann A, Fuh MM, Heeren J, Köhler N, Pauling JK, Klingenspor M. Dieckmann S, et al. Among authors: heeren j. Am J Physiol Endocrinol Metab. 2022 Feb 1;322(2):E85-E100. doi: 10.1152/ajpendo.00278.2021. Epub 2021 Dec 20. Am J Physiol Endocrinol Metab. 2022. PMID: 34927460 Free article.
Novel aspects of brown adipose tissue biology.
Heeren J, Münzberg H. Heeren J, et al. Endocrinol Metab Clin North Am. 2013 Mar;42(1):89-107. doi: 10.1016/j.ecl.2012.11.004. Epub 2012 Dec 12. Endocrinol Metab Clin North Am. 2013. PMID: 23391242 Free PMC article. Review.
Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development.
Berbée JF, Boon MR, Khedoe PP, Bartelt A, Schlein C, Worthmann A, Kooijman S, Hoeke G, Mol IM, John C, Jung C, Vazirpanah N, Brouwers LP, Gordts PL, Esko JD, Hiemstra PS, Havekes LM, Scheja L, Heeren J, Rensen PC. Berbée JF, et al. Among authors: heeren j. Nat Commun. 2015 Mar 10;6:6356. doi: 10.1038/ncomms7356. Nat Commun. 2015. PMID: 25754609 Free PMC article.
Implications of thermogenic adipose tissues for metabolic health.
Schlein C, Heeren J. Schlein C, et al. Among authors: heeren j. Best Pract Res Clin Endocrinol Metab. 2016 Aug;30(4):487-496. doi: 10.1016/j.beem.2016.08.002. Epub 2016 Aug 13. Best Pract Res Clin Endocrinol Metab. 2016. PMID: 27697210 Review.
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport.
Bartelt A, John C, Schaltenberg N, Berbée JFP, Worthmann A, Cherradi ML, Schlein C, Piepenburg J, Boon MR, Rinninger F, Heine M, Toedter K, Niemeier A, Nilsson SK, Fischer M, Wijers SL, van Marken Lichtenbelt W, Scheja L, Rensen PCN, Heeren J. Bartelt A, et al. Among authors: heeren j. Nat Commun. 2017 Apr 19;8:15010. doi: 10.1038/ncomms15010. Nat Commun. 2017. PMID: 28422089 Free PMC article. Clinical Trial.
Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis.
Worthmann A, John C, Rühlemann MC, Baguhl M, Heinsen FA, Schaltenberg N, Heine M, Schlein C, Evangelakos I, Mineo C, Fischer M, Dandri M, Kremoser C, Scheja L, Franke A, Shaul PW, Heeren J. Worthmann A, et al. Among authors: heeren j. Nat Med. 2017 Jul;23(7):839-849. doi: 10.1038/nm.4357. Epub 2017 Jun 12. Nat Med. 2017. PMID: 28604703
Metabolic Circuit Involving Free Fatty Acids, microRNA 122, and Triglyceride Synthesis in Liver and Muscle Tissues.
Chai C, Rivkin M, Berkovits L, Simerzin A, Zorde-Khvalevsky E, Rosenberg N, Klein S, Yaish D, Durst R, Shpitzen S, Udi S, Tam J, Heeren J, Worthmann A, Schramm C, Kluwe J, Ravid R, Hornstein E, Giladi H, Galun E. Chai C, et al. Among authors: heeren j. Gastroenterology. 2017 Nov;153(5):1404-1415. doi: 10.1053/j.gastro.2017.08.013. Epub 2017 Aug 9. Gastroenterology. 2017. PMID: 28802563
236 results