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CD137 (4-1BB) costimulation of CD8+ T cells is more potent when provided in cis than in trans with respect to CD3-TCR stimulation.
Otano I, Azpilikueta A, Glez-Vaz J, Alvarez M, Medina-Echeverz J, Cortés-Domínguez I, Ortiz-de-Solorzano C, Ellmark P, Fritzell S, Hernandez-Hoyos G, Nelson MH, Ochoa MC, Bolaños E, Cuculescu D, Jaúregui P, Sanchez-Gregorio S, Etxeberria I, Rodriguez-Ruiz ME, Sanmamed MF, Teijeira Á, Berraondo P, Melero I. Otano I, et al. Nat Commun. 2021 Dec 15;12(1):7296. doi: 10.1038/s41467-021-27613-w. Nat Commun. 2021. PMID: 34911975 Free PMC article.
The use of mixed collagen-Matrigel matrices of increasing complexity recapitulates the biphasic role of cell adhesion in cancer cell migration: ECM sensing, remodeling and forces at the leading edge of cancer invasion.
Anguiano M, Morales X, Castilla C, Pena AR, Ederra C, Martínez M, Ariz M, Esparza M, Amaveda H, Mora M, Movilla N, Aznar JMG, Cortés-Domínguez I, Ortiz-de-Solorzano C. Anguiano M, et al. PLoS One. 2020 Jan 16;15(1):e0220019. doi: 10.1371/journal.pone.0220019. eCollection 2020. PLoS One. 2020. PMID: 31945053 Free PMC article.
Heterogenous presence of neutrophil extracellular traps in human solid tumours is partially dependent on IL-8.
de Andrea CE, Ochoa MC, Villalba-Esparza M, Teijeira Á, Schalper KA, Abengozar-Muela M, Eguren-Santamaría I, Sainz C, Sánchez-Gregorio S, Garasa S, Ariz M, Ortiz-de-Solorzano C, Rodriguez-Ruiz ME, Perez-Gracia JL, Lozano MD, Echeveste JI, Sanmamed MF, Melero I. de Andrea CE, et al. J Pathol. 2021 Oct;255(2):190-201. doi: 10.1002/path.5753. Epub 2021 Aug 5. J Pathol. 2021. PMID: 34184758 Free article.
[No title available]
[No authors listed] [No authors listed] PMID: 35086922
96 results