Dumitrache LC - Search Results

1

Chromatin architecture at susceptible gene loci in cerebellar Purkinje cells characterizes DNA damage-induced neurodegeneration.

Kwak YD, Shaw TI, Downing SM, Tewari A, Jin H, Li Y, Dumitrache LC, Katyal S, Khodakhah K, Russell HR, McKinnon PJ. Kwak YD, et al. Among authors: dumitrache lc. Sci Adv. 2021 Dec 17;7(51):eabg6363. doi: 10.1126/sciadv.abg6363. Epub 2021 Dec 15. Sci Adv. 2021. PMID: 34910524 Free article.

2

Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability.

Shimada M, Dumitrache LC, Russell HR, McKinnon PJ. Shimada M, et al. Among authors: dumitrache lc. EMBO J. 2015 Oct 1;34(19):2465-80. doi: 10.15252/embj.201591363. Epub 2015 Aug 19. EMBO J. 2015. PMID: 26290337 Free PMC article.

3

Polynucleotide kinase-phosphatase (PNKP) mutations and neurologic disease.

Dumitrache LC, McKinnon PJ. Dumitrache LC, et al. Mech Ageing Dev. 2017 Jan;161(Pt A):121-129. doi: 10.1016/j.mad.2016.04.009. Epub 2016 Apr 26. Mech Ageing Dev. 2017. PMID: 27125728 Free PMC article. Review.

4

DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.

Enriquez-Rios V, Dumitrache LC, Downing SM, Li Y, Brown EJ, Russell HR, McKinnon PJ. Enriquez-Rios V, et al. Among authors: dumitrache lc. J Neurosci. 2017 Jan 25;37(4):893-905. doi: 10.1523/JNEUROSCI.4213-15.2016. J Neurosci. 2017. PMID: 28123024 Free PMC article.

5

Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors.

Dumitrache LC, Shimada M, Downing SM, Kwak YD, Li Y, Illuzzi JL, Russell HR, Wilson DM 3rd, McKinnon PJ. Dumitrache LC, et al. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12285-E12294. doi: 10.1073/pnas.1809682115. Epub 2018 Dec 11. Proc Natl Acad Sci U S A. 2018. PMID: 30538199 Free PMC article.

6

Out of LINE: Transposons, genome integrity, and neurodegeneration.

Dumitrache LC, McKinnon PJ. Dumitrache LC, et al. Neuron. 2022 Oct 19;110(20):3217-3219. doi: 10.1016/j.neuron.2022.09.026. Neuron. 2022. PMID: 36265437 Free article.

7

The dystonia gene THAP1 controls DNA double-strand break repair choice.

Shinoda K, Zong D, Callen E, Wu W, Dumitrache LC, Belinky F, Chari R, Wong N, Ishikawa M, Stanlie A, Multhaupt-Buell T, Sharma N, Ozelius L, Ehrlich M, McKinnon PJ, Nussenzweig A. Shinoda K, et al. Among authors: dumitrache lc. Mol Cell. 2021 Jun 17;81(12):2611-2624.e10. doi: 10.1016/j.molcel.2021.03.034. Epub 2021 Apr 14. Mol Cell. 2021. PMID: 33857404 Free PMC article.

8

53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.

Callen E, Zong D, Wu W, Wong N, Stanlie A, Ishikawa M, Pavani R, Dumitrache LC, Byrum AK, Mendez-Dorantes C, Martinez P, Canela A, Maman Y, Day A, Kruhlak MJ, Blasco MA, Stark JM, Mosammaparast N, McKinnon PJ, Nussenzweig A. Callen E, et al. Among authors: dumitrache lc. Mol Cell. 2020 Jan 2;77(1):26-38.e7. doi: 10.1016/j.molcel.2019.09.024. Epub 2019 Oct 22. Mol Cell. 2020. PMID: 31653568 Free PMC article.

9

Trex2 enables spontaneous sister chromatid exchanges without facilitating DNA double-strand break repair.

Dumitrache LC, Hu L, Son MY, Li H, Wesevich A, Scully R, Stark J, Hasty P. Dumitrache LC, et al. Genetics. 2011 Aug;188(4):787-97. doi: 10.1534/genetics.111.129833. Epub 2011 May 5. Genetics. 2011. PMID: 21546543 Free PMC article.

10

Biochemical and cellular characteristics of the 3' -> 5' exonuclease TREX2.

Chen MJ, Ma SM, Dumitrache LC, Hasty P. Chen MJ, et al. Among authors: dumitrache lc. Nucleic Acids Res. 2007;35(8):2682-94. doi: 10.1093/nar/gkm151. Epub 2007 Apr 10. Nucleic Acids Res. 2007. PMID: 17426129 Free PMC article.

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