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Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis.
Li Y, Schwabe RF, DeVries-Seimon T, Yao PM, Gerbod-Giannone MC, Tall AR, Davis RJ, Flavell R, Brenner DA, Tabas I. Li Y, et al. Among authors: schwabe rf. J Biol Chem. 2005 Jun 10;280(23):21763-72. doi: 10.1074/jbc.M501759200. Epub 2005 Apr 11. J Biol Chem. 2005. PMID: 15826936 Free article.
Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice.
Pradere JP, Kluwe J, De Minicis S, Jiao JJ, Gwak GY, Dapito DH, Jang MK, Guenther ND, Mederacke I, Friedman R, Dragomir AC, Aloman C, Schwabe RF. Pradere JP, et al. Among authors: schwabe rf. Hepatology. 2013 Oct;58(4):1461-73. doi: 10.1002/hep.26429. Epub 2013 Aug 9. Hepatology. 2013. PMID: 23553591 Free PMC article.
Hepatocyte Notch activation induces liver fibrosis in nonalcoholic steatohepatitis.
Zhu C, Kim K, Wang X, Bartolome A, Salomao M, Dongiovanni P, Meroni M, Graham MJ, Yates KP, Diehl AM, Schwabe RF, Tabas I, Valenti L, Lavine JE, Pajvani UB. Zhu C, et al. Among authors: schwabe rf. Sci Transl Med. 2018 Nov 21;10(468):eaat0344. doi: 10.1126/scitranslmed.aat0344. Sci Transl Med. 2018. PMID: 30463916 Free PMC article.
Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis.
Cai B, Dongiovanni P, Corey KE, Wang X, Shmarakov IO, Zheng Z, Kasikara C, Davra V, Meroni M, Chung RT, Rothlin CV, Schwabe RF, Blaner WS, Birge RB, Valenti L, Tabas I. Cai B, et al. Among authors: schwabe rf. Cell Metab. 2020 Feb 4;31(2):406-421.e7. doi: 10.1016/j.cmet.2019.11.013. Epub 2019 Dec 12. Cell Metab. 2020. PMID: 31839486 Free PMC article.
172 results