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A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells.
Mahoney M, Damalanka VC, Tartell MA, Chung DH, Lourenço AL, Pwee D, Mayer Bridwell AE, Hoffmann M, Voss J, Karmakar P, Azouz NP, Klingler AM, Rothlauf PW, Thompson CE, Lee M, Klampfer L, Stallings CL, Rothenberg ME, Pöhlmann S, Whelan SPJ, O'Donoghue AJ, Craik CS, Janetka JW. Mahoney M, et al. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2108728118. doi: 10.1073/pnas.2108728118. Proc Natl Acad Sci U S A. 2021. PMID: 34635581 Free PMC article.
Modulation of macrophage antitumor potential by apoptotic lymphoma cells.
Voss JJLP, Ford CA, Petrova S, Melville L, Paterson M, Pound JD, Holland P, Giotti B, Freeman TC, Gregory CD. Voss JJLP, et al. Cell Death Differ. 2017 Jun;24(6):971-983. doi: 10.1038/cdd.2016.132. Epub 2017 Feb 3. Cell Death Differ. 2017. PMID: 28157210 Free PMC article.
Oncogenic properties of apoptotic tumor cells in aggressive B cell lymphoma.
Ford CA, Petrova S, Pound JD, Voss JJ, Melville L, Paterson M, Farnworth SL, Gallimore AM, Cuff S, Wheadon H, Dobbin E, Ogden CA, Dumitriu IE, Dunbar DR, Murray PG, Ruckerl D, Allen JE, Hume DA, van Rooijen N, Goodlad JR, Freeman TC, Gregory CD. Ford CA, et al. Curr Biol. 2015 Mar 2;25(5):577-88. doi: 10.1016/j.cub.2014.12.059. Epub 2015 Feb 19. Curr Biol. 2015. PMID: 25702581 Free PMC article.