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Toward Individualized Prediction of Response to Methotrexate in Early Rheumatoid Arthritis: A Pharmacogenomics-Driven Machine Learning Approach.
Myasoedova E, Athreya AP, Crowson CS, Davis JM 3rd, Warrington KJ, Walchak RC, Carlson E, Kalari KR, Bongartz T, Tak PP, van Vollenhoven RF, Padyukov L, Emery P, Morgan A, Wang L, Weinshilboum RM, Matteson EL; Pharmacogenetics of Methotrexate in Rheumatoid Arthritis Consortium. Myasoedova E, et al. Among authors: tak pp. Arthritis Care Res (Hoboken). 2022 Jun;74(6):879-888. doi: 10.1002/acr.24834. Epub 2022 Apr 6. Arthritis Care Res (Hoboken). 2022. PMID: 34902228 Free article.
Genome-wide association study of response to methotrexate in early rheumatoid arthritis patients.
Taylor JC, Bongartz T, Massey J, Mifsud B, Spiliopoulou A, Scott IC, Wang J, Morgan M, Plant D, Colombo M, Orchard P, Twigg S, McInnes IB, Porter D, Freeston JE, Nam JL, Cordell HJ, Isaacs JD, Strathdee JL, Arnett D, de Hair MJH, Tak PP, Aslibekyan S, van Vollenhoven RF, Padyukov L, Bridges SL, Pitzalis C, Cope AP, Verstappen SMM, Emery P, Barnes MR, Agakov F, McKeigue P, Mushiroda T, Kubo M, Weinshilboum R, Barton A, Morgan AW, Barrett JH; MATURA; and PAMERA; Consortia. Taylor JC, et al. Among authors: tak pp. Pharmacogenomics J. 2018 Jul;18(4):528-538. doi: 10.1038/s41397-018-0025-5. Epub 2018 May 25. Pharmacogenomics J. 2018. PMID: 29795407 Free article. Review.
Early start and stop of biologics: has the time come?
van Vollenhoven RF, Nagy G, Tak PP. van Vollenhoven RF, et al. Among authors: tak pp. BMC Med. 2014 Feb 6;12:25. doi: 10.1186/1741-7015-12-25. BMC Med. 2014. PMID: 24502187 Free PMC article. Review.
Rheumatoid arthritis risk allele PTPRC is also associated with response to anti-tumor necrosis factor alpha therapy.
Cui J, Saevarsdottir S, Thomson B, Padyukov L, van der Helm-van Mil AH, Nititham J, Hughes LB, de Vries N, Raychaudhuri S, Alfredsson L, Askling J, Wedrén S, Ding B, Guiducci C, Wolbink GJ, Crusius JB, van der Horst-Bruinsma IE, Herenius M, Weinblatt ME, Shadick NA, Worthington J, Batliwalla F, Kern M, Morgan AW, Wilson AG, Isaacs JD, Hyrich K, Seldin MF, Moreland LW, Behrens TW, Allaart CF, Criswell LA, Huizinga TW, Tak PP, Bridges SL Jr, Toes RE, Barton A, Klareskog L, Gregersen PK, Karlson EW, Plenge RM. Cui J, et al. Among authors: tak pp. Arthritis Rheum. 2010 Jul;62(7):1849-61. doi: 10.1002/art.27457. Arthritis Rheum. 2010. PMID: 20309874 Free PMC article.
Sustained inhibition of progressive joint damage with rituximab plus methotrexate in early active rheumatoid arthritis: 2-year results from the randomised controlled trial IMAGE.
Tak PP, Rigby W, Rubbert-Roth A, Peterfy C, van Vollenhoven RF, Stohl W, Healy E, Hessey E, Reynard M, Shaw T. Tak PP, et al. Ann Rheum Dis. 2012 Mar;71(3):351-7. doi: 10.1136/annrheumdis-2011-200170. Epub 2011 Oct 19. Ann Rheum Dis. 2012. PMID: 22012969 Free PMC article. Clinical Trial.
Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39.
Spiliopoulou A, Colombo M, Plant D, Nair N, Cui J, Coenen MJ, Ikari K, Yamanaka H, Saevarsdottir S, Padyukov L, Bridges SL Jr, Kimberly RP, Okada Y, van Riel PLC, Wolbink G, van der Horst-Bruinsma IE, de Vries N, Tak PP, Ohmura K, Canhão H, Guchelaar HJ, Huizinga TW, Criswell LA, Raychaudhuri S, Weinblatt ME, Wilson AG, Mariette X, Isaacs JD, Morgan AW, Pitzalis C, Barton A, McKeigue P. Spiliopoulou A, et al. Among authors: tak pp. Ann Rheum Dis. 2019 Aug;78(8):1055-1061. doi: 10.1136/annrheumdis-2018-214877. Epub 2019 Apr 29. Ann Rheum Dis. 2019. PMID: 31036624 Free PMC article.
600 results