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RUNX1 transactivates BCR-ABL1 expression in Philadelphia chromosome positive acute lymphoblastic leukemia.
Masuda T, Maeda S, Shimada S, Sakuramoto N, Morita K, Koyama A, Suzuki K, Mitsuda Y, Matsuo H, Kubota H, Kato I, Tanaka K, Takita J, Hirata M, Kataoka TR, Nakahata T, Adachi S, Hirai H, Mizuta S, Naka K, Imai Y, Kimura S, Sugiyama H, Kamikubo Y. Masuda T, et al. Among authors: naka k. Cancer Sci. 2022 Feb;113(2):529-539. doi: 10.1111/cas.15239. Epub 2021 Dec 28. Cancer Sci. 2022. PMID: 34902205 Free PMC article.
Genetic regulation of the RUNX transcription factor family has antitumor effects.
Morita K, Suzuki K, Maeda S, Matsuo A, Mitsuda Y, Tokushige C, Kashiwazaki G, Taniguchi J, Maeda R, Noura M, Hirata M, Kataoka T, Yano A, Yamada Y, Kiyose H, Tokumasu M, Matsuo H, Tanaka S, Okuno Y, Muto M, Naka K, Ito K, Kitamura T, Kaneda Y, Liu PP, Bando T, Adachi S, Sugiyama H, Kamikubo Y. Morita K, et al. Among authors: naka k. J Clin Invest. 2017 Jun 30;127(7):2815-2828. doi: 10.1172/JCI91788. Epub 2017 May 22. J Clin Invest. 2017. PMID: 28530640 Free PMC article.
HMGCLL1 is a predictive biomarker for deep molecular response to imatinib therapy in chronic myeloid leukemia.
Park JH, Woo YM, Youm EM, Hamad N, Won HH, Naka K, Park EJ, Park JH, Kim HJ, Kim SH, Kim HJ, Ahn JS, Sohn SK, Moon JH, Jung CW, Park S, Lipton JH, Kimura S, Kim JW, Kim DDH. Park JH, et al. Among authors: naka k. Leukemia. 2019 Jun;33(6):1439-1450. doi: 10.1038/s41375-018-0321-8. Epub 2018 Dec 16. Leukemia. 2019. PMID: 30555164 Free PMC article.
Creation of Philadelphia chromosome by CRISPR/Cas9-mediated double cleavages on BCR and ABL1 genes as a model for initial event in leukemogenesis.
Tamai M, Fujisawa S, Nguyen TTT, Komatsu C, Kagami K, Kamimoto K, Omachi K, Kasai S, Harama D, Watanabe A, Akahane K, Goi K, Naka K, Kaname T, Teshima T, Inukai T. Tamai M, et al. Among authors: naka k. Cancer Gene Ther. 2023 Jan;30(1):38-50. doi: 10.1038/s41417-022-00522-w. Epub 2022 Aug 23. Cancer Gene Ther. 2023. PMID: 35999358 Free PMC article.
580 results