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Single center, open label dose escalating trial evaluating once weekly oral ixazomib in ART-suppressed, HIV positive adults and effects on HIV reservoir size in vivo.
Cummins NW, Baker J, Chakraborty R, Dean PG, Garcia-Rivera E, Krogman A, Kumar S, Kuzmichev YV, Laird GM, Landay A, Lichterfeld M, Mahmood M, Martinson J, Maynes M, Natesampillai S, Rajkumar V, Rassadkina Y, Ritter KD, Rivera CG, Rizza SA, Subramanian K, Tande AJ, Wonderlich ER, Whitaker JA, Zeuli J, Badley AD. Cummins NW, et al. Among authors: lichterfeld m. EClinicalMedicine. 2021 Nov 29;42:101225. doi: 10.1016/j.eclinm.2021.101225. eCollection 2021 Dec. EClinicalMedicine. 2021. PMID: 34901797 Free PMC article.
Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study.
Cummins NW, Rizza S, Litzow MR, Hua S, Lee GQ, Einkauf K, Chun TW, Rhame F, Baker JV, Busch MP, Chomont N, Dean PG, Fromentin R, Haase AT, Hampton D, Keating SM, Lada SM, Lee TH, Natesampillai S, Richman DD, Schacker TW, Wietgrefe S, Yu XG, Yao JD, Zeuli J, Lichterfeld M, Badley AD. Cummins NW, et al. Among authors: lichterfeld m. PLoS Med. 2017 Nov 28;14(11):e1002461. doi: 10.1371/journal.pmed.1002461. eCollection 2017 Nov. PLoS Med. 2017. PMID: 29182633 Free PMC article.
Antiretroviral Therapy Reduces T-cell Activation and Immune Exhaustion Markers in Human Immunodeficiency Virus Controllers.
Li JZ, Segal FP, Bosch RJ, Lalama CM, Roberts-Toler C, Delagreverie H, Getz R, Garcia-Broncano P, Kinslow J, Tressler R, Van Dam CN, Keefer M, Carrington M, Lichterfeld M, Kuritzkes D, Yu XG, Landay A, Sax PE; AIDS Clinical Trials Group Study A5308 Team. Li JZ, et al. Among authors: lichterfeld m. Clin Infect Dis. 2020 Apr 10;70(8):1636-1642. doi: 10.1093/cid/ciz442. Clin Infect Dis. 2020. PMID: 31131858 Free PMC article. Clinical Trial.
Distinct viral reservoirs in individuals with spontaneous control of HIV-1.
Jiang C, Lian X, Gao C, Sun X, Einkauf KB, Chevalier JM, Chen SMY, Hua S, Rhee B, Chang K, Blackmer JE, Osborn M, Peluso MJ, Hoh R, Somsouk M, Milush J, Bertagnolli LN, Sweet SE, Varriale JA, Burbelo PD, Chun TW, Laird GM, Serrao E, Engelman AN, Carrington M, Siliciano RF, Siliciano JM, Deeks SG, Walker BD, Lichterfeld M, Yu XG. Jiang C, et al. Among authors: lichterfeld m. Nature. 2020 Sep;585(7824):261-267. doi: 10.1038/s41586-020-2651-8. Epub 2020 Aug 26. Nature. 2020. PMID: 32848246 Free PMC article.
Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia.
Collins DR, Urbach JM, Racenet ZJ, Arshad U, Power KA, Newman RM, Mylvaganam GH, Ly NL, Lian X, Rull A, Rassadkina Y, Yanez AG, Peluso MJ, Deeks SG, Vidal F, Lichterfeld M, Yu XG, Gaiha GD, Allen TM, Walker BD. Collins DR, et al. Among authors: lichterfeld m. Immunity. 2021 Oct 12;54(10):2372-2384.e7. doi: 10.1016/j.immuni.2021.08.007. Epub 2021 Sep 7. Immunity. 2021. PMID: 34496223 Free PMC article.
A Possible Sterilizing Cure of HIV-1 Infection Without Stem Cell Transplantation.
Turk G, Seiger K, Lian X, Sun W, Parsons EM, Gao C, Rassadkina Y, Polo ML, Czernikier A, Ghiglione Y, Vellicce A, Varriale J, Lai J, Yuki Y, Martin M, Rhodes A, Lewin SR, Walker BD, Carrington M, Siliciano R, Siliciano J, Lichterfeld M, Laufer N, Yu XG. Turk G, et al. Among authors: lichterfeld m. Ann Intern Med. 2022 Jan;175(1):95-100. doi: 10.7326/L21-0297. Epub 2021 Nov 16. Ann Intern Med. 2022. PMID: 34781719 Free PMC article.
Immune correlates of HIV-1 reservoir cell decline in early-treated infants.
Hartana CA, Garcia-Broncano P, Rassadkina Y, Lian X, Jiang C, Einkauf KB, Maswabi K, Ajibola G, Moyo S, Mohammed T, Maphorisa C, Makhema J, Yuki Y, Martin M, Bennett K, Jean-Philippe P, Viard M, Hughes MD, Powis KM, Carrington M, Lockman S, Gao C, Yu XG, Kuritzkes DR, Shapiro R, Lichterfeld M. Hartana CA, et al. Among authors: lichterfeld m. Cell Rep. 2022 Jul 19;40(3):111126. doi: 10.1016/j.celrep.2022.111126. Cell Rep. 2022. PMID: 35858580 Free PMC article.
HIV-1 reservoir evolution in infants infected with clade C from Mozambique.
Koofhethile CK, Rinaldi S, Rassadkina Y, Dinh VB, Gao C, Pallikkuth S, Garcia-Broncano P, de Armas LR, Pahwa R, Cotugno N, Vaz P, Lain MG, Palma P, Yu XG, Shapiro R, Pahwa S, Lichterfeld M. Koofhethile CK, et al. Among authors: lichterfeld m. Int J Infect Dis. 2023 Feb;127:129-136. doi: 10.1016/j.ijid.2022.11.042. Epub 2022 Dec 5. Int J Infect Dis. 2023. PMID: 36476348 Free PMC article.
178 results